纳米硅和水溶性硅酸盐对肝脏的影响(与文献数据对比)

Evgeniia A. Grigoreva, V. Gordova, V. Sergeeva
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引用次数: 1

摘要

本文综述了近十年来国内外研究人员对硅类化合物——纳米硅和水溶性硅酸盐对人体影响的研究结果。无定形二氧化硅在现代工业中的广泛使用,以及俄罗斯联邦关于饮用水中硅含量的规范性文件的修订,使这方面具有特殊的相关性。我们自己对实验动物摄入硅与饮用水的长期实验结果与文献数据进行了比较。研究表明,暴露于水溶性硅酸盐和纳米颗粒引起的肝脏形态变化是相似的。因此,硅的生物惰性、工业硅使用监测、饮用水中硅的最大允许浓度调整等问题需要进一步研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
THE EFFECT OF SILICON NANOPARTICLES AND WATER-SOLUBLE SILICATES ON THE LIVER (COMPARISON OF OUR OWN RESEARCH RESULTS WITH THE LITERATURE DATA)
This literature review combines data on the effect of silicon compounds on the body – silicon nanoparticles and water-soluble silicates, obtained by domestic and foreign researchers over the past decade. a widespread use of amorphous silicon dioxide in modern industry, as well as revision of regulatory documents on silicon content in drinking water in the Russian Federation give this aspect special relevance. Increased attention is paid to comparing our own results of long-term experiments on silicon intake with drinking water by laboratory animals and the literature data. It has been shown that morphological changes in the liver caused by exposure to water-soluble silicates and nanoparticles are similar. Thus, questions about the biological inertness of silicon, monitoring the use of silicon in industry, and adjustment of its maximum permissible concentration in drinking water require further study.
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