基于自适应局部区域拟合能量模型的宫颈涂片图像无监督细胞核分割

Ziming Zeng, Siping Chen, Sheng Tang, Lidong Yin
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引用次数: 4

摘要

本文提出了一种基于自适应活动轮廓建模的宫颈涂片图像细胞核分割方法。该方法的基本思想是使轮廓自适应变形,从而得到给定区域能量函数的最小值。为了减少轮廓演化对强度均匀性的依赖,达到细胞核自适应分割的目的,该方法利用形态学方法对活动轮廓建模进行初始化。然后利用高斯核函数提取局部区域,并定义其局部区域拟合能量函数,在局部区域内逼近轮廓两侧的图像强度。最后,采用Split Bregman方法得到鲁棒数值解并生成分割结果。在我们的实验中,与一些现有的方法相比,该方法可以获得准确的分割结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Unsupervised segmentation of cell nuclei in cervical smear images using active contour with adaptive local region fitting energy modelling
In this paper, we propose a method based on an adaptive active contour modelling to segment the cell nuclei from cervical smear images. The basic idea of our method is to make a contour to adaptively deform so as to get a minimized given region energy function. In order to make the evolution of the contour rely less on the intensity homogeneity and achieve the purpose of adaptive segmentation of the cell nuclei, the proposed method utilizes the morphology method to initialize the active contour modelling. Then a Gaussian kernel function is used to extract the local region and defines its local region fitting energy function which approximates the image intensities on the two sides of the contour in the local region. Finally, the Split Bregman method is used to obtain a robust numerical solution and to generate the segmentation results. In our experiments, the proposed approach can obtain accurate segmentation results compared with some state-of-the-art approaches.
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