65岁以上的癌症患者入院重症监护

C. Sirjacques, Lieveke Ameye, T. Berghmans, M. Paesmans, J. Sculier, A. Meert
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摘要

关于入住重症监护病房(ICU)的老年癌症患者生存率的数据很少。本研究的目的是评估我科年龄≥≥≥65岁患者住院死亡率和出院后生存的预后因素。患者和方法:回顾性研究,纳入2012年1月1日至2014年12月31日在肿瘤科ICU因急性并发症收治的所有≥≥≥65例实体或血液肿瘤患者。结果:270例患者共311例入院。入院的主要原因是心血管(22%)、呼吸(17%)和血流动力学(13%)。ICU和住院死亡率分别为10%和22%。确定的医院死亡率较高的独立预后因素是使用无创通气(NIV)或使用有创机械通气(IMV)以及在最初24小时内存在治疗限制。出院后,死亡的独立预后因素为Charlson评分≥≥≥≥8,SAPS II评分e > 37,第1小时内使用胺类药物。总共77%的患者在出院后能够从抗肿瘤治疗中获益。结论:维持生命治疗限制直接关系到住院死亡率和出院后生存率。然而,绝大多数人仍然能够从癌症治疗中受益。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Les patients âgés de plus de 65 ans atteints d'un cancer admis aux soins intensifs
Introduction : There is very little data on the survival of elderly patients with cancer admitted to intensive care unit (ICU). The aim of the study is to evaluate in our department prognostic factors for hospital mortality and survival after hospital discharge for patients aged ≥≥≥≥≥ 65 years. Patients and Methods : Retrospective study including all patients ≥≥≥≥≥ 65 with a solid or hematological tumor admitted for an acute complication in an oncological ICU from 01/01/2012 to 31/12/2014. Results : We recorded 311 admissions for 270 patients. The main reasons for admission were cardiovascular (22 %), respiratory (17 %) and hemodynamic (13 %). ICU and in-hospital mortality rates were respectively 10 % and 22 %. The identified independent prognostic factors for higher hospital mortality were the use of non invasive ventilation (NIV) use or of invasive mechanical ventilation (IMV) use and the existence of a therapeutic limitation in the first 24 hours. After hospital discharge, independent prognostic factors for death were Charlson’s score ≥≥≥≥≥ 8, SAPS II score e» 37, administration of amines in the first first hours. A total of 77 % of patients were able to benefit from an antineoplastic treatment after hospital discharge.Conclusion : Life-sustaining therapeutic limitation is directly related to hospital mortality and post-discharge survival. However, the large majority was still able to benefit from cancer treatment.
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