局部氧疗对糖尿病伴富尼耶坏疽创面愈合的影响

A. Saeed, Aamir Abdullah, Rehman Maqbool, J. Iqbal
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引用次数: 0

摘要

背景:在所有高危人群中,伴有富尼尔坏疽的糖尿病患者死亡率最高。目的:比较辅助表面氧治疗方法和常规方法在糖尿病富尼耶坏疽患者治疗中的疗效。方法:这是一项比较横断面研究,于2020年1月1日至6月30日在费萨拉巴德联合医院外科3单元进行。本研究采用系统随机抽样的方法,共纳入120例通过门诊或急诊科就诊的患者。A组在常规方法的基础上给予局部氧疗。B组仅采用常规创面护理方法。在A组,100%的氧气在一个袋子里,常规可用的氧气瓶暴露整个身体或肢体的影响部分。连续7 - 10天,每天两次,每次最多给氧一个半小时。在循环之间的间隔,伤口被浸透的消毒敷料覆盖。临床改善后,患者出院,并要求在室外随访,最初每周一次,然后每两周随访一次,直至6个月。结果:a组平均年龄36.45±10岁,B组平均年龄35.38±9岁。辅助表面氧治疗与常规方法治疗富尼耶坏疽的疗效比较,a组有效率44例(73.3%),b组有效率29例(48.3%)(p=0.00)。结论:辅助表面氧疗治疗富尼耶坏疽的疗效明显高于常规治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of Topical Oxygen Therapy on Wound Healing in Diabetic Patients with Fournier's Gangrene
Background: Diabetic patients presenting with Fournier gangrene have the highest mortality rate of all at-risk populations. Objective: To compare the efficacy of adjuvant topical oxygen therapy methods and conventional methods in the management of diabetic patients having Fournier's gangrene Methodology: This was a comparative cross-sectional study, in Surgical unit 3, Allied Hospital, Faisalabad, from 1st January to 30th June 2020. A total of 120 cases were included by systematic random sampling in the study, who were admitted either through OPD or the Emergency ward. In Group A, Topical Oxygen Therapy was given along with conventional methods. In Group B only conventional methods of wound care were applied. In group A, 100% oxygen was given in a bag with a routinely available oxygen cylinder exposing the whole affected part of the body or limb. Oxygen in the chamber was given for a maximum of one and a half hours twice daily in one sitting for 7 to 10 days. In the interval between cycles, the wound was covered with a soaked antiseptic dressing. After clinical improvement, the patient was discharged and called for follow-up in outdoor on weekly intervals initially and then fortnightly for up to 6 months. Results: Mean age was calculated as 36.45±10 and 35.38±9 years in Group-A and B respectively. Comparison of the efficacy of adjuvant topical oxygen therapy and conventional methods in the management of Fournier’s gangrene showed that 44 (73.3%) in Group-A and 29 (48.3%) in Group-B had efficacy (p=0.00). Conclusion: Efficacy of adjuvant topical oxygen therapy is significantly higher when compared with conventional methods in the management of Fournier's gangrene.
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