结构性生活方式改变对2型糖尿病心血管危险因素的影响:一项随机对照试验

NM Lamu, SL Pitmang, DJ Meshak, NT Ishaya, J. Anejo-Okopi, J. Madaki
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引用次数: 0

摘要

一些临床试验表明,改变生活方式可以降低血压,影响体重和血脂,降低心血管疾病的风险因素。该研究评估了在Jos大学教学医院(JUTH)普通门诊(GOPC)就诊的2型糖尿病患者中,有组织的生活方式改变对心血管危险因素的影响。该研究是一项随机对照试验,从2015年10月到2016年2月,352名参与者参加了JUTH GOPC的研究。提供的干预措施是在为期12周的时间里,就饮食和运动方面的结构性生活方式改变提供咨询。主要结局指标是血压、体重和血脂的变化。使用Epi Info 3.5.3版本对数据进行分析。干预组在两组间有显著差异;平均收缩压-65 mmHg (t = 5.344;P = 0.017),平均体重-1.78kg (t = 2.452;P = 0.015)。在乔斯大学教学医院普通门诊就诊的2型糖尿病患者中,有组织的生活方式改变对可改变的心血管危险因素有显著改善。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effects of Structured lifestyle Modification on Cardiovascular Risk Factors in Type-2 Diabetes Mellitus: A Randomized Controlled Trial
Several clinical trials have shown that lifestyle modifications lower blood pressure, affect weight as well as lipid profile and lower risk factors for cardiovascular diseases. The study assessed the effect of structured lifestyle modification on cardiovascular risk factors amongst type 2 diabetic patients that attend the General Outpatient Clinic (GOPC) of Jos University Teaching Hospital (JUTH). The study was a randomized controlled trial on 352 participants at the GOPC of JUTH, from October 2015 to February 2016. The intervention offered was counselling on structured lifestyle modification in diet and exercise for a period of 12 weeks. The primary outcome measures were changes in blood pressure, weight and lipid profile. The data were analyzed using Epi Info version 3.5.3. There were significant differences between groups in favor of the intervention group; mean systolic blood pressure of -65 mmHg (t = 5.344; p = 0.017) and mean weight of -1.78kg (t = 2.452; p = 0.015). Structured lifestyle modification caused significant improvement on modifiable cardiovascular risk factors in patients with type 2 diabetes mellitus attending the general outpatient clinic of the Jos University Teaching Hospital.
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