基于异构最早完成时间的数字微流控生物芯片调度

Rajesh Kolluri, J. Kumar, Sumanta Pyne
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引用次数: 4

摘要

芯片实验室(Lab-on-chip, LOC)技术是生化分析领域的新兴技术之一,它利用数字微流体特性对液滴进行离散操作。LOC在一个称为数字微流控生物芯片(DMFB)的可重构芯片上有效地执行我们在传统实验室中进行的所有生化操作。与使用的样品和设备相比,DMFBs有助于实现并行化和小型化。DMFB合成中的一个重要问题是调度问题。我们提出了一种简单的方法,称为数字微流体的异构最早完成时间(DMHEFT)来调度数字微流体。它是一种基于贪婪启发式的列表调度方法。HEFT以前用于任务调度,其中多个异构处理器可用于解决DAG描述的相互依赖的任务。本文将其应用于微流控生物芯片。DMHEFT使用向上排序值来确定任务或操作的优先级,并使用最早完成时间将任务分配给不同的模块,如混合器、加热器和检测器等。仿真结果表明,与现有算法相比,该算法产生了更好的分析长度和运行时间。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Heterogeneous Earliest Finish Time based Scheduling for Digital Microfluidic Biochips
One of the recent emerging technology in biochemical analysis field is Lab-on-chip (LOC) technology which uses digital microfluidics property to manipulate droplets discretely. LOC efficiently carries out all biochemical operations we do in traditional laboratories on a single reconfigurable chip called as Digital Microfluidic Biochip (DMFB). DMFBs helps to achieve parallelism and miniaturization compared to traditional laboratory methods in terms of samples and equipment used. One of the important problem in DMFB synthesis is scheduling. We present a simple method called as Heterogeneous Earliest Finish Time for digital microfluidics (DMHEFT) for scheduling DMFB. It is a greedy heuristic based list scheduling. HEFT is previously used for task scheduling where multiple heterogeneous processors are available for solving inter-dependent tasks depicted as DAG. In this paper, it is applied to Microfluidic biochips. DMHEFT uses Upward rank value to prioritize the tasks or operations and earliest finish time to assign tasks to different modules like mixers, heaters and detectors etc. Simulation results show that it produces better assay lengths and run time compared to existing algorithms.
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