{"title":"t细胞非霍奇金淋巴瘤的临床特点、治疗及预后分析","authors":"Y. Miao, Qiaojiajie Zhao","doi":"10.58195/amr.v1i1.12","DOIUrl":null,"url":null,"abstract":"Objective: Regarding T-cell non-Hodgkin's lymphoma, it is important to explore both its clinical characteristics and treatment methods, as well as to make a good prognostic analysis. Methods: From 2017.02 to 2022.02, 40 patients with T-cell non-Hodgkin's lymphoma were seen in our hospital, and their data were implemented retrospectively. RESULTS: According to certain indicators of patients, they were divided into low-risk group (0-1 factors), low-medium-risk group (2 factors), high-medium-risk group (3 factors), and high-risk group (4-5 factors); after first-line treatment, the 3-year overall survival rates of patients with CR, PR, SD, and PD were 71%, 46%, 0%, and 0%, respectively; after treatment with CHOP-like regimens and other chemotherapy regimens, CR, PR, SD, and PD patients had 5-year overall survival rates of 44%, 36%, 0%, and 0%, respectively; after first-line treatment, CR patients were 16, PR patients were 16, and the effective rate was 80%, and SD+PD was 8. The CHOP-like regimen was used to treat 9 patients with CR, 9 patients with PR, 6 patients with SD, and 4 patients with PD; other chemotherapy regimens were used to treat 2 patients with CR, 4 patients with PR, 3 patients with SD, and 3 patients with PD, with an efficiency rate of 60% and an inefficiency rate of 40%. Conclusion: T-cell non-Hodgkin's lymphoma is easy to be misdiagnosed, and the prognosis analysis should be explored according to its clinical characteristics, combined with the treatment regimen, in order to ensure a significant treatment effect.","PeriodicalId":202943,"journal":{"name":"Advanced Medical Research","volume":"16 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Clinical features, Treatment and Prognosis Analysis of T-cell non-Hodgkin's Lymphoma\",\"authors\":\"Y. Miao, Qiaojiajie Zhao\",\"doi\":\"10.58195/amr.v1i1.12\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective: Regarding T-cell non-Hodgkin's lymphoma, it is important to explore both its clinical characteristics and treatment methods, as well as to make a good prognostic analysis. Methods: From 2017.02 to 2022.02, 40 patients with T-cell non-Hodgkin's lymphoma were seen in our hospital, and their data were implemented retrospectively. RESULTS: According to certain indicators of patients, they were divided into low-risk group (0-1 factors), low-medium-risk group (2 factors), high-medium-risk group (3 factors), and high-risk group (4-5 factors); after first-line treatment, the 3-year overall survival rates of patients with CR, PR, SD, and PD were 71%, 46%, 0%, and 0%, respectively; after treatment with CHOP-like regimens and other chemotherapy regimens, CR, PR, SD, and PD patients had 5-year overall survival rates of 44%, 36%, 0%, and 0%, respectively; after first-line treatment, CR patients were 16, PR patients were 16, and the effective rate was 80%, and SD+PD was 8. The CHOP-like regimen was used to treat 9 patients with CR, 9 patients with PR, 6 patients with SD, and 4 patients with PD; other chemotherapy regimens were used to treat 2 patients with CR, 4 patients with PR, 3 patients with SD, and 3 patients with PD, with an efficiency rate of 60% and an inefficiency rate of 40%. Conclusion: T-cell non-Hodgkin's lymphoma is easy to be misdiagnosed, and the prognosis analysis should be explored according to its clinical characteristics, combined with the treatment regimen, in order to ensure a significant treatment effect.\",\"PeriodicalId\":202943,\"journal\":{\"name\":\"Advanced Medical Research\",\"volume\":\"16 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-08-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advanced Medical Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.58195/amr.v1i1.12\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced Medical Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.58195/amr.v1i1.12","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Clinical features, Treatment and Prognosis Analysis of T-cell non-Hodgkin's Lymphoma
Objective: Regarding T-cell non-Hodgkin's lymphoma, it is important to explore both its clinical characteristics and treatment methods, as well as to make a good prognostic analysis. Methods: From 2017.02 to 2022.02, 40 patients with T-cell non-Hodgkin's lymphoma were seen in our hospital, and their data were implemented retrospectively. RESULTS: According to certain indicators of patients, they were divided into low-risk group (0-1 factors), low-medium-risk group (2 factors), high-medium-risk group (3 factors), and high-risk group (4-5 factors); after first-line treatment, the 3-year overall survival rates of patients with CR, PR, SD, and PD were 71%, 46%, 0%, and 0%, respectively; after treatment with CHOP-like regimens and other chemotherapy regimens, CR, PR, SD, and PD patients had 5-year overall survival rates of 44%, 36%, 0%, and 0%, respectively; after first-line treatment, CR patients were 16, PR patients were 16, and the effective rate was 80%, and SD+PD was 8. The CHOP-like regimen was used to treat 9 patients with CR, 9 patients with PR, 6 patients with SD, and 4 patients with PD; other chemotherapy regimens were used to treat 2 patients with CR, 4 patients with PR, 3 patients with SD, and 3 patients with PD, with an efficiency rate of 60% and an inefficiency rate of 40%. Conclusion: T-cell non-Hodgkin's lymphoma is easy to be misdiagnosed, and the prognosis analysis should be explored according to its clinical characteristics, combined with the treatment regimen, in order to ensure a significant treatment effect.