全球药品获取:一场艰苦的斗争

C. Ndayishimiye, Desmond A. Aji
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引用次数: 0

摘要

背景:本研究源于作者的卫生技术评价与合理的药物政策课程。目的:通过提供不同的背景和促进人口获得药物的可能解决办法或缓解战略,回答是否存在全球获得药物的问题。方法:对纸质资料进行专题内容分析(TCA)。结果:共纳入文献39篇,包括22篇文章,11篇技术报告,2本书,1本书章节,3个网站。药物可及性问题影响到四大类药物——基本药物、创新药物、孤儿药和高价药物。然而,由于一些原因,包括专利,这些药物的获取受到阻碍;过高的成本;波动的生产;罕见病市场无利可图;创新疗法的延误,即使在发达国家也是如此。结论:促进药品可及性的努力应针对所有部门——公共、私营和非政府部门——并应与制药公司和主要卫生保健机构建立联系。*本研究源于作者为欧洲公共卫生硕士课程所做的“卫生技术评估和合理药物政策”课程:欧洲公共卫生+研究,该课程由欧盟伊拉斯谟+计划资助。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Global access to medicines: An uphill struggle
Background: The study originated from the authors’ coursework in health technology assessment and rational pharmaceutical policy. Purpose: To respond to the question of whether there is a global problem of access to medications by providing differentiated backgrounds and possible solutions or mitigation strategies for boosting the population’s access to medications. Method: Thematic content analysis (TCA) was performed on paper-based data. Findings: 39 documents were included, including 22 articles, eleven technical reports, two books, one book chapter, and three websites. Drug accessibility issues affect four major categories – essential, innovative, orphan, and highly-priced medicines. Access to these medications is nevertheless hampered for several reasons, including patents; prohibitive costs; fluctuating production; market unprofitability for rare diseases; and delays in innovative treatments, even in developed countries. Conclusion: Efforts to boost drug access should target all sectors – public, private, and non-governmental – and should forge ties with pharmaceutical firms and key health care institutions. * This study arose from the authors’ coursework “Health Technology Assessment and Rational Pharmaceutical Policy” for the European Public Health Master: Europubhealth+ Studies, which was funded by the European Union’s Erasmus+ Program.
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