溴化咪唑及其co (ii)、cu (ii)、mn (ii)、ni (ii)和zn (ii)配合物的合成和抗菌性能评价

E. D. O., Ngochindo R. I., Odokuma, L. O., E. O. C
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引用次数: 1

摘要

合成了2,4,5 -三溴咪唑(tbi),并用波谱方法对其结构进行了表征。合成了co(ii)、cu(ii)、mn(ii)、ni(ii)和zn(ii)配合物,并对大肠杆菌、蜡样芽孢杆菌cf7、苏云金杆菌eb151、铜绿假单胞菌335k55、铜绿假单胞菌pg1和白色念珠菌进行了抑菌活性评价。这些化合物对两种假单胞菌均无抑菌作用,抑菌作用顺序为:tbi > cu[tbi] > cr[tbi] > ni[tbi] > mn[tbi] > zn[tbi] > co[tbi]。所有金属离子的络合作用都降低了tbi的活性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
SYNTHESES AND ANTIMICROBIAL EVALUATION OF BROMINATED IMIDAZOLE AND ITS CO (II), CU(II), MN(II), NI(II), AND ZN(II) COMPLEXES
2, 4, 5-tribromoimidazole (tbi) was synthesized and its structure was elucidated using spectroscopic methods. its co(ii), cu(ii), mn(ii), ni(ii), and zn(ii) complexes were synthesized and their antimicrobial activities were evaluated against escherichia coli, bacillus cereus strain cf7, bacillus thuringensis strain eb151, pseudomonas aeruginosa strain 335k55, pseudomonas aeruginosa strain pg1, and candida albicans. these compounds were all inactive to both strains of pseudomonas spp. antimicrobial activities of these compounds is found to be in the order tbi > cu[tbi] > cr[tbi] > ni[tbi] > mn[tbi] > zn[tbi] > co[tbi]. the activity of tbi was reduced upon complexation by all the metal ions used.
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