粒子治疗加速器的未来展望

S. Myers, A. Degiovanni, J. Farr
{"title":"粒子治疗加速器的未来展望","authors":"S. Myers, A. Degiovanni, J. Farr","doi":"10.1142/s1793626819300056","DOIUrl":null,"url":null,"abstract":"Particle therapy is the expanding radiotherapy treatment option of choice for cancer. Its cost, however, is currently hindering its worldwide expansion. Also, the ideal application of particle therapy is restricted by a series of unsolved technical challenges. Both the cost and technical limitations are directly traceable to dependence on legacy accelerators and their associated treatment possibilities. This chapter is written to address these needs. Firstly, a technical overview is presented of photon and particle therapy for cancer tumours. Secondly, the underlying limitations of the existing legacy systems are identified, especially those related to accelerators, and suggestions are made for current and future developments to address these shortcomings. The legacy systems referred to here are of the slow scanning variety using large, circular accelerators. This paper also attempts to make a scientific comparison of the various types of accelerators currently used or being developed for particle therapy. The following procedure is pursued to perform a comparison between various types of accelerators: (1) The parameters which are pertinent to particle therapy accelerators (‘specified parameters’) are identified from clinical efficiency and overall cost considerations. (2) The range and values of ‘specified parameters’ associated with each type of particle therapy accelerator are identified. (3) A comparison is made on the best match between the various types of accelerators for each of the ‘specified parameters,’ i.e., the best in class accelerator, when compared to each criterion. (4) Based on this match, an overall conclusion is made on the type of accelerator which best fits the needs for particle therapy.","PeriodicalId":376234,"journal":{"name":"Reviews of Accelerator Science and Technology","volume":"143 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":"{\"title\":\"Future Prospects for Particle Therapy Accelerators\",\"authors\":\"S. Myers, A. Degiovanni, J. Farr\",\"doi\":\"10.1142/s1793626819300056\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Particle therapy is the expanding radiotherapy treatment option of choice for cancer. Its cost, however, is currently hindering its worldwide expansion. Also, the ideal application of particle therapy is restricted by a series of unsolved technical challenges. Both the cost and technical limitations are directly traceable to dependence on legacy accelerators and their associated treatment possibilities. This chapter is written to address these needs. Firstly, a technical overview is presented of photon and particle therapy for cancer tumours. Secondly, the underlying limitations of the existing legacy systems are identified, especially those related to accelerators, and suggestions are made for current and future developments to address these shortcomings. The legacy systems referred to here are of the slow scanning variety using large, circular accelerators. This paper also attempts to make a scientific comparison of the various types of accelerators currently used or being developed for particle therapy. The following procedure is pursued to perform a comparison between various types of accelerators: (1) The parameters which are pertinent to particle therapy accelerators (‘specified parameters’) are identified from clinical efficiency and overall cost considerations. (2) The range and values of ‘specified parameters’ associated with each type of particle therapy accelerator are identified. (3) A comparison is made on the best match between the various types of accelerators for each of the ‘specified parameters,’ i.e., the best in class accelerator, when compared to each criterion. (4) Based on this match, an overall conclusion is made on the type of accelerator which best fits the needs for particle therapy.\",\"PeriodicalId\":376234,\"journal\":{\"name\":\"Reviews of Accelerator Science and Technology\",\"volume\":\"143 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Reviews of Accelerator Science and Technology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1142/s1793626819300056\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Reviews of Accelerator Science and Technology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1142/s1793626819300056","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 4

摘要

粒子疗法是癌症放射治疗的扩展选择。然而,它的成本目前阻碍了它在全球的扩张。此外,粒子治疗的理想应用受到一系列未解决的技术挑战的限制。成本和技术限制都可以直接追溯到对传统加速器及其相关处理可能性的依赖。本章就是为了满足这些需求而写的。本文首先介绍了光子和粒子治疗肿瘤的技术概况。其次,确定了现有遗留系统的潜在局限性,特别是与加速器相关的局限性,并对当前和未来的发展提出了建议,以解决这些缺点。这里提到的遗留系统是使用大型圆形加速器的慢扫描系统。本文还试图对目前使用或正在开发的用于粒子治疗的各种类型的加速器进行科学比较。以下程序是为了对不同类型的加速器进行比较:(1)与粒子治疗加速器相关的参数(“指定参数”)是从临床效率和总体成本考虑中确定的。(2)确定与每种粒子治疗加速器相关的“指定参数”的范围和值。(3)比较不同类型的加速器与每个“指定参数”之间的最佳匹配,即与每个标准进行比较时的同类最佳加速器。(4)在此基础上,得出了最适合粒子治疗需要的加速器类型的总体结论。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Future Prospects for Particle Therapy Accelerators
Particle therapy is the expanding radiotherapy treatment option of choice for cancer. Its cost, however, is currently hindering its worldwide expansion. Also, the ideal application of particle therapy is restricted by a series of unsolved technical challenges. Both the cost and technical limitations are directly traceable to dependence on legacy accelerators and their associated treatment possibilities. This chapter is written to address these needs. Firstly, a technical overview is presented of photon and particle therapy for cancer tumours. Secondly, the underlying limitations of the existing legacy systems are identified, especially those related to accelerators, and suggestions are made for current and future developments to address these shortcomings. The legacy systems referred to here are of the slow scanning variety using large, circular accelerators. This paper also attempts to make a scientific comparison of the various types of accelerators currently used or being developed for particle therapy. The following procedure is pursued to perform a comparison between various types of accelerators: (1) The parameters which are pertinent to particle therapy accelerators (‘specified parameters’) are identified from clinical efficiency and overall cost considerations. (2) The range and values of ‘specified parameters’ associated with each type of particle therapy accelerator are identified. (3) A comparison is made on the best match between the various types of accelerators for each of the ‘specified parameters,’ i.e., the best in class accelerator, when compared to each criterion. (4) Based on this match, an overall conclusion is made on the type of accelerator which best fits the needs for particle therapy.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信