N. Ozana, A. Peruch, Mitchell B. Robinson, Dibbyan Mazumder, M. Blackwell, N. Lue, S. Carp, M. Franceschini
{"title":"时间门控漫射相关光谱在1064nm脉冲激光整形和超导纳米线单光子传感功能成像中的应用","authors":"N. Ozana, A. Peruch, Mitchell B. Robinson, Dibbyan Mazumder, M. Blackwell, N. Lue, S. Carp, M. Franceschini","doi":"10.1117/12.2578909","DOIUrl":null,"url":null,"abstract":"Recently, we developed a time-domain diffuse correlation spectroscopy (TD-DCS) method for neurovascular sensing with higher brain sensitivity. In this paper, laser pulse shaping was designed and demonstrated for TD-DCS at 1064 nm. A quantum superconducting nanowire single-photon detector (SNSPD) with high photon detection efficiency (PDE) and low jitter collects the back-scattered light from the brain. The presented approach is the first step towards scaling up a full fiber optic cap with 96 source channels and 192 custom-made single-photon detectors which will cover most of an adult head.","PeriodicalId":189801,"journal":{"name":"Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics","volume":"21 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2021-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Time-gated diffuse correlation spectroscopy for functional imaging via 1064 nm pulse laser shaping and superconducting nanowire single photon sensing\",\"authors\":\"N. Ozana, A. Peruch, Mitchell B. Robinson, Dibbyan Mazumder, M. Blackwell, N. Lue, S. Carp, M. Franceschini\",\"doi\":\"10.1117/12.2578909\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Recently, we developed a time-domain diffuse correlation spectroscopy (TD-DCS) method for neurovascular sensing with higher brain sensitivity. In this paper, laser pulse shaping was designed and demonstrated for TD-DCS at 1064 nm. A quantum superconducting nanowire single-photon detector (SNSPD) with high photon detection efficiency (PDE) and low jitter collects the back-scattered light from the brain. The presented approach is the first step towards scaling up a full fiber optic cap with 96 source channels and 192 custom-made single-photon detectors which will cover most of an adult head.\",\"PeriodicalId\":189801,\"journal\":{\"name\":\"Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics\",\"volume\":\"21 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-03-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1117/12.2578909\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1117/12.2578909","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Time-gated diffuse correlation spectroscopy for functional imaging via 1064 nm pulse laser shaping and superconducting nanowire single photon sensing
Recently, we developed a time-domain diffuse correlation spectroscopy (TD-DCS) method for neurovascular sensing with higher brain sensitivity. In this paper, laser pulse shaping was designed and demonstrated for TD-DCS at 1064 nm. A quantum superconducting nanowire single-photon detector (SNSPD) with high photon detection efficiency (PDE) and low jitter collects the back-scattered light from the brain. The presented approach is the first step towards scaling up a full fiber optic cap with 96 source channels and 192 custom-made single-photon detectors which will cover most of an adult head.