硅酸盐掺杂合成柔性生物材料力学性能研究

Ihsan Coskun, O. Karaman
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引用次数: 0

摘要

生物材料在组织再生中发挥着积极的作用,被广泛应用于组织移植治疗,用于修复受损硬组织、骨癌、骨骼创伤和感染导致的骨质流失、骨折以及面部和颅骨的先天性畸形。由于自体骨移植和同种异体骨移植有许多缺点,因此需要人工骨移植和生物材料。许多生物陶瓷材料如β -磷酸三钙(β - tcp)和硫酸钙被广泛应用于骨形成。由于基于β - tcp的骨移植物以颗粒的形式使用,硅酸盐增强的柔性条用于骨科手术,口腔和颌面外科。本研究的目的是研究硅酸盐掺杂柔性生物材料的力学性能,考虑其生物相容性及其对组织再生的积极影响。为了达到所述的目的,计划遵循的方法,拉伸试验将应用于扫描电子显微镜(SEM)图像的力学性能,用于其形态学。本研究发现,硅酸掺杂柔性生物材料具有均匀多孔的结构。此外,根据ISO(国际标准化组织)5833和ASTM(美国试验与材料学会)D638标准,证明了所获得的力学测试结果和硅酸盐掺杂柔性生物材料在骨再生中的功能。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Investigation of Mechanical Properties of Silicate Doped Synthetic Flexible Biomaterial
Biomaterials play an active role in tissue regeneration and are widely used in the treatment of tissue transplantation applications for the repair of damaged hard tissue, bone cancer, bone loss due to skeletal trauma and infection, bone fractures and congenital deformities of the facial and skull bones. Since autografts and allografts have many disadvantages, there is a need for synthetic bone grafts and biomaterials. Many bioceramic materials such as beta-tricalcium phosphate (beta-TCP) and calcium sulfate are widely used in bone formation. Since beta-TCP-based bone grafts are used in the form of granules, silicate reinforced flexible strips are used in orthopedic surgery, oral and maxillofacial surgery. The aim of this study is to examine the mechanical properties of silicate-doped flexible biomaterials, taking into account their biocompatibility and their positive effects on tissue regeneration. In order to achieve the stated purpose, the methods planned to be followed, tensile tests will be applied for the mechanical properties of the scanning electron microscope (SEM) image for its morphology. In this study, it was found that silicate-doped flexible biomaterials have a homogeneous and porous structure. In addition, the obtained mechanical test results and the functionality of the silicate-doped flexible biomaterial during bone regeneration according to the ISO (International Organization for Standardization) 5833 and ASTM (American Society for Testing and Materials) D638 standard have been demonstrated.
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