3-氨基苯基硼酸修饰氧化石墨烯检测糖化血红蛋白

V. SivaRamaKrishna, B. Amrutur, N. Bhat, K. ChakraPani, S. Srinivasan
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引用次数: 9

摘要

本文介绍了3-氨基苯基硼酸(APBA)修饰氧化石墨烯(GO)的化学合成及其在糖化血红蛋白(GHb)电化学检测中的应用。通过在APBA的氨基(-NH2)和GO的羧基(-COOH)之间形成酰胺键合成了GO-APBA化合物。用红外光谱对化合物进行了表征。以GO-APBA修饰的玻碳电极为工作电极,采用电化学阻抗谱法(EIS)检测GHb。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Detection of glycated hemoglobin using 3-Aminophenylboronic acid modified graphene oxide
This paper presents the chemical synthesis of 3-Aminophenylboronic acid (APBA) modified graphene oxide (GO) and its application to the electrochemical detection of glycated hemoglobin (GHb). The compound (GO-APBA) was synthesized by forming an amide linkage between the amino group (-NH2) of APBA and the carboxylic group (-COOH) of GO. The compound was characterized using IR spectroscopy. Detection of GHb was carried out using Electrochemical Impedance Spectroscopic (EIS) measurements with GO-APBA modified glassy carbon electrode as the working electrode.
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