病例报告:一例罕见的脓皮坏疽性鼻中隔穿孔

Mohammed, Al-Tayyar, A. Toma
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引用次数: 0

摘要

背景:坏疽脓皮病(Pyoderma gangrenosum, PG)是一种罕见的皮肤非感染性中性粒细胞疾病,通常影响下肢,并与炎症性肠病相关。极少数情况下,它可以影响鼻中隔,引起鼻中隔穿孔。方法:我们回顾了一例已知患有PG并持续鼻中隔穿孔的52岁男性患者,并回顾了他的血液检查、计算机断层扫描结果和组织学结果。结果:排除其他常见病因后,确诊为PG所致鼻中隔穿孔。鼻鳞状黏膜广泛溃疡,伴有炎性肉芽组织和脓肿样区域,进一步支持了这一点。这些结果与组织学报告的PG诊断一致。结论:虽然继发于PG的鼻中隔穿孔被认为是罕见的,但这种表现仍然应该被记住,特别是当其他可能的鼻中隔穿孔原因已经被排除,并且PG已经得到了很好的证实。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Case report: a rare presentation of nasal septal perforation due to pyoderma gangrenosum
Background: Pyoderma gangrenosum (PG) is a rare dermatologic non-infectious neutrophilic disease that classically affects the lower extremities and is associated with inflammatory bowel disease. Rarely, it could affect the nasal septum, causing nasal septal perforation. Methods: We reviewed the case of a 52-year-old male patient known to have PG with ongoing nasal septal perforation and reviewed his blood tests, computed tomography scan findings and histologic results. Results: A diagnosis of nasal septal perforation due to PG was confirmed after exclusion of other common aetiologies. This was further supported by the presence of extensive ulceration of the nasal squamous mucosa with inflamed granulation tissue and abscess-like areas. These findings were consistent with the diagnosis of PG based on the histology report. Conclusion: Although nasal septal perforation secondary to PG is considered rare, this presentation should still be kept in mind, especially when other possible causes of nasal septal perforation have been excluded and PG has been already well established.
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