编者注:医学微生物学与诊断

J. Weltman
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引用次数: 0

摘要

El-Banna等人研究了抗组胺药物对革兰氏阴性菌耐药适应性的影响。乙醇胺类抗组胺药苯海拉明与阿奇霉素、红霉素、阿米卡星、庆大霉素、环丙沙星等多种抗生素联用对多药耐药肺炎克雷伯菌的增效作用显著。这一信息可用于治疗传染病,特别是在这个出现多重耐药菌株的时代。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Editor Note: Medical Microbiology & Diagnosis
Research by El-Banna et al. studied the effects of antihistamine drugs on adaptations of Gram-negative bacteria to resist antimicrobial agents were investigated. Marked synergism was detected in multidrug resistant (MDR) Klebsiella pneumoniae isolates when the ethanolamine antihistaminic, diphenhydramine, was used in combination with a variety of antibiotics such as azithromycin, erythromycin, amikacin, gentamicin or ciprofloxacin. This information can be useful in the treatment of infectious diseases, especially in this era of emerging multi-drug resistant strains [2].
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