胆固醇在老年人认知功能中的作用

V. Deshpande, Vishwin Doda
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引用次数: 0

摘要

与其他与血脂异常有关的病理相比,胆固醇在认知能力下降中的作用鲜为人知。然而,众所周知,胆固醇在大脑正常功能和衰老过程中具有多种功能。因此,这项研究旨在发现胆固醇与年龄相关的认知能力下降之间的相互关系。评估受试者的认知功能,并将其与各自的血胆固醇水平进行比较。该研究包括来自马哈拉施特拉邦的50名老年受试者(女性:12%),使用马拉地语版迷你精神状态检查(MMSE)进行评估,并使用血脂调查获得他们的胆固醇血浓度。然后使用统计分析将胆固醇水平和认知功能相互关联。总胆固醇和低密度脂蛋白胆固醇较高的受试者在迷你精神状态检查(MMSE)测试中的得分略低。然而,这种差异被发现是显著的。根据所获得的结果,没有发现血胆固醇水平与认知功能之间的相关关系
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Role of cholesterol in cognitive function in the elderly
The role of cholesterol in Cognitive Decline is less known as compared to other pathologies linked with dyslipidaemia. However, Cholesterol is well-known to have multiple functions in normal functioning of the brain and the aging process. This study therefore aimed at finding a co-relation, if any, between Cholesterol and age-related cognitive decline.To assess Cognitive Function of subjects and compare it with respective blood cholesterol levels. The study included 50 elderly subjects from Maharashtra (females: 12%) assessed using Marathi version of Mini Mental State Examination (MMSE) and their cholesterol blood concentrations obtained using a Lipid Profile investigation. Cholesterol levels and cognitive function was then co-related using statistical analysis.The subjects with a higher Total Cholesterol & LDL Cholesterol had slightly less scores on the Mini Mental State Examination (MMSE) Test. However, the difference was found to be significant.Based on the results obtained, no relevant co-relation could be found between Blood Cholesterol Levels and Cognitive Function
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