潜在的癌症生物标志物

Fathima Mohammed Ahamed, Asiya Nazir
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引用次数: 0

摘要

肿瘤学领域的广泛研究能够识别具有肿瘤特异性分子特征的潜在癌症生物标志物,这些分子特征超过或补充了现有的生物标志物。然而,由于所涉及的生物学过程的复杂性,在癌症生物标志物的开发和临床验证中存在挑战。广泛的生物分子及其表达模式、表观遗传改变和代谢作用的单独或综合方法在癌症研究中得到了很好的研究。潜在的癌症生物标志物需要通过先进的技术进行广泛的研究,从而给癌症的筛查和治疗带来巨大的变化。本章概述了潜在癌症生物标志物的最新研究。此外,还讨论了三种常见类型癌症中潜在生物标志物的具体特征。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Potential Cancer Biomarkers
Extensive studies in the field of oncology are able to identify potential cancer biomarkers with tumor-specific molecular characteristics that exceed or complement those of existing biomarkers. However, there are challenges in the development and clinical validation of the cancer biomarkers due to the complexity of the biological process involved. Standalone or integrative approach of broad range of biomolecules, their expression pattern, epigenetic alterations, and metabolic effects are well studied in the cancer research. The potential cancer biomarkers need to be studied extensively with advanced technologies to bring about a great change in cancer screening and therapy. This chapter provide an overview on recent studies about potential cancer biomarkers. Also, specific characteristics of potential biomarkers in three common types of cancer are discussed.
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