Geremia B. Bolli, Francesca Porcellati, P. Lucidi, Carmine G. Fanelli
{"title":"30年前,DCCT的结果——当时的意义和今天的意义","authors":"Geremia B. Bolli, Francesca Porcellati, P. Lucidi, Carmine G. Fanelli","doi":"10.30682/ildia2302d","DOIUrl":null,"url":null,"abstract":"The DCCT (Diabetes Control Complication Trials) has conclusively demonstrated in 1993 that good glycaemic control prevents the micro-angiopathy caused by chronic hyperglycaemia in T1DM. The subsequent follow-up study EDIC (Epidemiology of Diabetes Interventions and Complications) has demonstrated similar results for macro-angiopathy. Taken together, DCCT and EDIC strongly indicate the need for aggressive treatment of T1DM with intensive therapy to target near-normoglycaemia since clinical onset of T1DM to prevent long-term micro- and macro-vascular complications. Today and in the years to come, this message remains and will remain as fundamental as it was 30 years ago. \n","PeriodicalId":119243,"journal":{"name":"Il Diabete","volume":"107 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Trent’anni fa i risultati del DCCT: cosa significarono allora e cosa rappresentano oggi\",\"authors\":\"Geremia B. Bolli, Francesca Porcellati, P. Lucidi, Carmine G. Fanelli\",\"doi\":\"10.30682/ildia2302d\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The DCCT (Diabetes Control Complication Trials) has conclusively demonstrated in 1993 that good glycaemic control prevents the micro-angiopathy caused by chronic hyperglycaemia in T1DM. The subsequent follow-up study EDIC (Epidemiology of Diabetes Interventions and Complications) has demonstrated similar results for macro-angiopathy. Taken together, DCCT and EDIC strongly indicate the need for aggressive treatment of T1DM with intensive therapy to target near-normoglycaemia since clinical onset of T1DM to prevent long-term micro- and macro-vascular complications. Today and in the years to come, this message remains and will remain as fundamental as it was 30 years ago. \\n\",\"PeriodicalId\":119243,\"journal\":{\"name\":\"Il Diabete\",\"volume\":\"107 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-07-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Il Diabete\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.30682/ildia2302d\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Il Diabete","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.30682/ildia2302d","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Trent’anni fa i risultati del DCCT: cosa significarono allora e cosa rappresentano oggi
The DCCT (Diabetes Control Complication Trials) has conclusively demonstrated in 1993 that good glycaemic control prevents the micro-angiopathy caused by chronic hyperglycaemia in T1DM. The subsequent follow-up study EDIC (Epidemiology of Diabetes Interventions and Complications) has demonstrated similar results for macro-angiopathy. Taken together, DCCT and EDIC strongly indicate the need for aggressive treatment of T1DM with intensive therapy to target near-normoglycaemia since clinical onset of T1DM to prevent long-term micro- and macro-vascular complications. Today and in the years to come, this message remains and will remain as fundamental as it was 30 years ago.