转铁蛋白、铁及一些生化指标在肥胖男性中的作用

Mohammed N. Mahmmod, E. Sarhat
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引用次数: 0

摘要

肥胖是一种持续的疾病,其特征是脂肪组织的非典型或过度堆积,导致健康受损,发病率和慢性健康问题的可能性增加。几十年来,全球肥胖和超重人群的发病率一直在上升。该研究的目的是确定肥胖男性身体质量指数(BMI)、胰岛素、转铁蛋白、铁和血脂之间的关系。研究招募了90名男性;40名参与者被分为肥胖组,BMI>30 kg/m2, 20名参与者被分为超重组,BMI在25-30 kg/m2之间,另外30名参与者被分为对照组,BMI<25 kg/m2。测定各组血清转铁蛋白、空腹胰岛素、血清铁、血脂和空腹血糖。肥胖组血清胰岛素浓度较对照组显著升高(16.77±7.68∶11.7±2.79,p <0.001)。此外,在转铁蛋白和脂质谱检测显著变化。三组间铁和葡萄糖浓度无显著差异。血清转铁蛋白结合血清铁和血清铁蛋白可作为肥胖患者缺铁标志物参与未来的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Role of Transferrin, Iron and Some Biochemical Variables in Obese Males
The condition of obesity is a persistent ailment characterized by the atypical or excessive buildup of adipose tissue, resulting in compromised well-being and an elevated likelihood of morbidity and chronic health issues. The global incidence of individuals with obesity and overweight conditions has been on the rise for numerous decades. The goal of the study is to identify the relationship between body mass index (BMI), insulin, transferrin, iron, and lipid profile in obese males. Ninety males were recruited into the study; forty participants were assigned to the obese group were have BMI>30 kg/m2, twenty to overweight group were have BMI between 25-30 kg/m2, and another thirty to the control group were have slow BMI<25 kg/m2. The serum Transferrin, serum fasting insulin, serum iron, lipid profile and fasting glucose was evaluated in each of studied groups. The Obese group showed significant increase of the serum insulin concentration compared with the control group (16.77±7.68 vs. 11.7 ±2.79, p <0.001). As well as in transferrin and lipid profile significant change was detected. No prominent differences were detected in the three groups in iron and glucose concentration. Investigation of serum transferrin can be participated in future as iron deficiency marker in obese subject in conjugation with serum iron and serum ferritin.
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