G. Panda, P. N. Narasimha Murthy, Iswori Prasad Padhy, Ghanshyam Panigrahi
{"title":"麝香花果皮甲醇提取物的抗腹泻和抗运动活性研究","authors":"G. Panda, P. N. Narasimha Murthy, Iswori Prasad Padhy, Ghanshyam Panigrahi","doi":"10.46624/ajphr.2018.v6.i8.001","DOIUrl":null,"url":null,"abstract":"The objective of the present study was investigation of antidiarrhoeal and antimotility activities of methanolic extract of musa sapientum (familyMusaceae) flowers and fruit peels. The phytochemical analysis of both extracts of Musa sapientum revealed the presence of alkaloids, carbohydrates, glycosides, saponins, proteins, coumarins, flavonoids, triterpenoids, tannins and phenolic compounds. The extracts were evaluated for castor oilinduced diarrhoea and intestinal motility test in rats. Both the methanolic extracts were significantly (p<0.05) and dose dependently reduced frequency of stooling in castor oil-induced diarrhoea and anti-motility action in intestinal motility test. These findings suggest that the methanolic extract of the musa sapientum flowers and fruit peels may contain some biologically active ingredients that are useful for the treatment of diarrhoea.","PeriodicalId":233230,"journal":{"name":"American Journal of Pharmacy And Health Research","volume":"299 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2018-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Investigation of Antidiarrhoeal and Antimotility Activities of Methanolic Extract of Musa Sapientum Flowers and Fruit Peels\",\"authors\":\"G. Panda, P. N. Narasimha Murthy, Iswori Prasad Padhy, Ghanshyam Panigrahi\",\"doi\":\"10.46624/ajphr.2018.v6.i8.001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The objective of the present study was investigation of antidiarrhoeal and antimotility activities of methanolic extract of musa sapientum (familyMusaceae) flowers and fruit peels. The phytochemical analysis of both extracts of Musa sapientum revealed the presence of alkaloids, carbohydrates, glycosides, saponins, proteins, coumarins, flavonoids, triterpenoids, tannins and phenolic compounds. The extracts were evaluated for castor oilinduced diarrhoea and intestinal motility test in rats. Both the methanolic extracts were significantly (p<0.05) and dose dependently reduced frequency of stooling in castor oil-induced diarrhoea and anti-motility action in intestinal motility test. These findings suggest that the methanolic extract of the musa sapientum flowers and fruit peels may contain some biologically active ingredients that are useful for the treatment of diarrhoea.\",\"PeriodicalId\":233230,\"journal\":{\"name\":\"American Journal of Pharmacy And Health Research\",\"volume\":\"299 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-08-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"American Journal of Pharmacy And Health Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.46624/ajphr.2018.v6.i8.001\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"American Journal of Pharmacy And Health Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.46624/ajphr.2018.v6.i8.001","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Investigation of Antidiarrhoeal and Antimotility Activities of Methanolic Extract of Musa Sapientum Flowers and Fruit Peels
The objective of the present study was investigation of antidiarrhoeal and antimotility activities of methanolic extract of musa sapientum (familyMusaceae) flowers and fruit peels. The phytochemical analysis of both extracts of Musa sapientum revealed the presence of alkaloids, carbohydrates, glycosides, saponins, proteins, coumarins, flavonoids, triterpenoids, tannins and phenolic compounds. The extracts were evaluated for castor oilinduced diarrhoea and intestinal motility test in rats. Both the methanolic extracts were significantly (p<0.05) and dose dependently reduced frequency of stooling in castor oil-induced diarrhoea and anti-motility action in intestinal motility test. These findings suggest that the methanolic extract of the musa sapientum flowers and fruit peels may contain some biologically active ingredients that are useful for the treatment of diarrhoea.