本土制备的间歇性负压伤口敷料:在印度情况下有效和经济

Aayushi Choudhary, M. Joshi, Nitesh Lamoria
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摘要

简介:间歇性负压伤口治疗(INPWT)是一种经过验证的加速伤口愈合的方法,通过增加血流量,促进血管生成和基质金属蛋白酶的吸力去除。本研究的目的是评估INPWT在压疮中的应用。在我们的研究中,我们使用了非常低成本的本地材料用于INPWT,以取代市售的昂贵的真空辅助封闭(VAC)机器和敷料。材料与方法:本研究是在某三级医院整形重建外科和物理医学与康复科进行的前瞻性研究。我们治疗了80例脊髓损伤患者,其中70%为亚洲A级和B级压疮,最常见于骶骨和坐骨区,国家压疮咨询委员会3级和4级压疮。纳入的患者包括57名男性和23名女性。该研究采用了当地制造的低成本材料,如泡沫、Ioban胶带、Room Vac引流和吸引机(在当地任何一级、二级和三级保健中心都很容易获得),用于压疮患者的INPWT。每4天更换一次敷料,直至形成所需的肉芽组织。结果:在接受INPWT治疗的患者中,30%的患者实现了直接闭合,49%的患者需要裂皮移植,21%的患者需要局部皮瓣重建。市场上的商用VAC机价格在30 - 50万印度卢比左右,单次梳妆费用在7000 - 1.5万印度卢比左右。这可能在经济上不可行,特别是对于有大伤口的患者,需要多次使用这些敷料和我们的本土敷料;服装的价格下降了95%-98%。结论:该研究得出结论,低成本的本土制备的INPWT敷料以最低的成本产生了与市售的昂贵的VAC敷料相当的有效效果。这种低成本的本土制备的INPWT在印度等发展中国家的农村和城市环境中治疗压疮患者方面具有开创性意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Indigenously prepared intermittent negative pressure wound dressing: Effective and economic in Indian scenario
Introduction: Intermittent negative pressure wound treatment (INPWT) is a proven way to accelerate wound healing by increasing blood flow, promoting angiogenesis and suction removal of matrix metalloproteinases. The purpose of the study was to evaluate the use of INPWT in pressure sores. In our study, we have used very low-cost locally available material for INPWT in place of commercially available costly vacuum-assisted closure (VAC) machine and dressing. Materials and Methods: This was a prospective study conducted in the department of plastic and reconstruction surgery and physical medicine and rehabilitation at a tertiary level facility. Eighty patients of spinal cord injury with 70% of ASIA Grade A and B with pressure ulcer most commonly at sacral and ischial regions with National Pressure Ulcer Advisory Panel Grade 3 and Grade 4 pressure sore were treated. Patients enrolled included 57 males and 23 females. The study employed locally manufactured low-cost materials such as foam, Ioban tape, Room Vac drain and suction machine (easily and locally available at any primary, secondary as well as tertiary healthcare centre) for INPWT in patients with pressure sores. Dressing was changed every 4th day till desired granulation tissue was formed. Results: Out of patients who were treated with INPWT, 30% achieved direct closure, 49% required split skin grafting and 21% required reconstruction by local flaps. Commercial available VAC machines available in the market cost around 300,000–500,000 INR, and the cost of single dressing is around 7000–15,000 INR. This may not be economically feasible, especially in patients having large wounds which require multiple applications of these dressings with our indigenous dressing; there is a 95%–98% decrease in pricing of dressing. Conclusion: The study concluded that low-cost indigenously prepared INPWT dressing produced effective results at minimum cost that were at par with commercially available costly VAC dressing. This low-cost indigenously prepared INPWT can be groundbreaking in treatment of patients with pressure ulcer in developing country like India in both rural and urban settings.
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