Damian Osahon Emwanta, R. Ngochindo, L. Odokuma, O. Eruteya
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EVALUATION OF THE MICROBIAL TOXICITIES OF 4, 5-DICHLOROIMIDAZOLE AND ITS MN (II), NI (II), AND ZN (II) COMPLEXES
4, 5-Dichloroimidazole (4,5-DCI) was synthesized, recrystallized from water and characterized using spectroscopic methods. It was screened for its antimicrobial activities against five bacterial strains namely: Escherichia coli, Bacillus cereus strain CF7, Bacillus thuringensis strain EB151, Pseudomonas aeruginosa strain 335K55, and Pseudomonas aeruginosa strain PG1. These microorganisms were very sensitive to the compound. Their sensitivities were increased appreciably by the Ni2+ and Mn2+ complexes of 4,5-dichloroimidazole and reduced by its Zn2+ complex. The sensitivities of these microorganisms towards these compounds were higher than their sensitivities towards Levofloxacin – a reference antibacterial.
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