微生物在癌症进展和DNA损伤效应中的影响

Adnan Shahid, Sajid Ali, Tazeeem Zahra, M. Raza, Attra Shahid, M. U. Saeed, Faria Javaid
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引用次数: 16

摘要

病毒利用宿主细胞的成分来完成它的生命周期。有些病毒会导致或促成癌症的发展。与引起急性感染的其他病毒(如流感病毒)不同,致瘤病毒通常会引起长期持续感染。几项研究还涉及不同微生物引起的癌症进展中的毒性。微生物及其代谢副产物,或慢性炎症的影响,也可能与口腔癌有关。幽门螺杆菌在人的胃和十二指肠中定植。在某些情况下,它会导致胃癌。伤寒沙门氏菌已被证实与胆囊癌有关,但它也可能有助于为治疗黑色素瘤、结肠癌和膀胱癌提供化疗药物。皂苷降低了老年癌症发生的风险。它有一种特殊的结构,能有效地对抗癌细胞。微生物的浓度和攻击能力以及其他病原体与化合物的浓度直接相关,例如通过饮食作为正确成分的皂苷。皂苷在其他方面起到抗氧化剂的作用来预防癌症。当癌细胞攻击正常细胞时,癌细胞转移的过程就很难停止。皂苷还显示出对肺部因某种原因而受到攻击的无功能细胞的活性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Influence of Microbes in Progression of Cancer and DNA Damaging Effects
Virus uses components of the host cell to complete its life cycle. Some viruses can cause or contribute to the development of cancer. Unlike other viruses, such as influenza viruses, that cause an acute infection, oncogenic viruses often cause long-term, persistent infections. Several studies also involved in the toxicity in progression of cancer caused by different microbes. Microorganisms and their metabolic byproducts, or impact of chronic inflammation, may also be linked to oral cancers. Helicobacter pylori colonize the human stomach and duodenum. In some cases it can cause stomach cancer. Salmonella Typhi has been linked to gallbladder cancer but may also be useful in delivering chemotherapeutic agents for the treatment of melanoma, colon and bladder cancer. Saponins reduced the risks of the occurring of the cancer during advanced age. It has special structure that active for the frightening against the cells of the cancer. The concentrations and attacking power of the microbes as well as the other pathogens directly related to the concentration of the compounds such as the saponins that taken through diet as the right composition. Saponins in other way acting as the antioxidants to prevent the cancer. When the cells of the cancer attacked on the normal one then became difficult to stop the process of the metastasis. Saponins also showed activity against the nonfunctional cells of the lungs that have been attacked due to certain cause’s cancer.
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