Joko Pitoyo, Bambang S Noegroho, Ricky Adriansjah
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摘要

良性前列腺增生(BPH)治疗的目标是缓解症状和维持疾病进展,以及药物的副作用及其对改善生活质量和性质量的益处。本研究旨在评估坦索罗辛治疗与坦索罗辛与度他雄胺联合治疗对前列腺增生引起LUTS男性勃起硬度评分(EHS)的影响。本研究是一项横断面研究,评估和比较坦索罗新治疗和坦索罗新+杜他雄胺联合治疗前后良性前列腺增生(BPH)患者勃起硬度评分(EHS)的差异。治疗3个月后,坦索罗辛组IPSS评分为12.87 (p=0.00), IIEF-5评分为15.43 (p=0.51), EHS评分为2.6 (p=0.08);坦索罗辛+度他asteride组IPSS评分为12.53(p=0.00), IIEF-5评分为15.83 (p=0.02), EHS评分为2.6 (p=0.01)。与坦索罗新单药治疗相比,坦索罗新+杜他胺联合治疗EHS的降低在统计学上更为显著,这是由于每种药物联合治疗的效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Penilaian Erection Hardness Score Pasien Benign Prostatic Hyperplasia yang Ditangani dengan Tamsulosin dan Kombinasi Tamsulosin-Dutasteride
The goal of Benign Prostate Hyperplasia (BPH) therapy is to relieve symptoms and maintain disease progression as well as the side effects of drugs and their benefits for improving the quality of life and sexual quality. This study aimed to assess the effect of tamsulosin therapy with combination therapy of tamsulosin and dutasteride on the erection hardness score (EHS) in men with LUTS due to BPH. This study is a cross-sectional study which assesses and compares differences in erection hardness scores (EHS) of patients with benign prostatic hyperplasia (BPH) before and after tamsulosin therapy and the combination of tamsulosin + dutasteride. After three months of therapy, the group of subjects given tamsulosin had an IPSS score of 12.87 (p=0.00), IIEF-5 15.43 (p=0.51), EHS 2.6 (p=0.08), while the tamsulosin + dutasteride group had an IPSS score 12.53(p=0.00), IIEF-5 15.83 (p=0.02), and EHS 2.6 (p=0.01). The decrease in EHS was more statistically significant in treatment with tamsulosin + dutasteride combination therapy compared with tamsulosin monotherapy, this was due to the effect of each drug combined.
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