黄疸和微型血管

L. Hattenbach
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引用次数: 0

摘要

目的:本研究的目的是评价光学相干断层血管造影(OCTA)特征的患者成功接受黄斑孔(MH)手术。方法:选取19例因MH行单眼手术的患者和13例健康对照者作为研究对象。采用OCTA检测对照组右眼、手术眼和健康眼视网膜浅、深毛细血管丛血管密度、血流指数和中央凹无血管带(FAZ)面积。结果:手术眼浅、深毛细血管丛平均血管密度明显低于对照组(分别为44.1比49.6%,p = 0.002和47.3比59.1%,p = 0.009)。手术眼浅层和深层毛细血管流动指数均值显著低于对照组(分别为0.85比1.35,p = 0.003和0.57比1.45,p = 0.001),手术眼浅层和深层FAZ面积均值显著高于对照组(分别为0.55比0.32,p < 0.001和0.64比0.37,p = 0.001)。健康者两层眼流量指标与对照组无显著差异。结论:这些初步结果可能是手术后视力不理想的原因,尽管手术成功地闭合了MH。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Makulaforamen und Mikrogefäße
Purpose: The aim of this study was to evaluate the optical coherence tomography angiography (OCTA) features of patients who underwent successful macular hole (MH) surgery. Methods: Nineteen patients who underwent surgery in a single eye due to MH and 13 healthy subjects as a control group were included in the study. Vascular densities, flow indexes, and the foveal avascular zone (FAZ) area in superficial and deep retinal capillary plexuses were evaluated by OCTA in the right eyes of the control group, and both the surgical and healthy fellow eyes of the patients. Results: The mean vascular densities of the superficial and deep capillary plexuses were significantly lower in the surgical eyes than in the control group (44.1 vs. 49.6%, p = 0.002, and 47.3 vs. 59.1%, p = 0.009, respectively). The mean superficial and deep capillary flow indexes were significantly lower in the surgical eyes than in the control group (0.85 vs. 1.35, p = 0.003, and 0.57 vs. 1.45, p = 0.001, respectively), while the mean superficial and deep FAZ area were significantly greater in the surgical eyes in comparison to the control group (0.55 vs. 0.32, p < 0.001, and 0.64 vs. 0.37, p = 0.001, respectively). There was no difference between the flow indexes of both layers of the healthy fellow eyes and the control group. Conclusions: These preliminary results may be an explanation for unsatisfactory visual gain after surgery, despite the successful anatomical closure of the MH.
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