类风湿膝关节全膝关节置换术的外科治疗选择综述

Sergiu-Andrei Iordache, B. Șerban, M. Popa, A. Cursaru
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摘要

类风湿性关节炎(RA)是一种可以侵蚀软骨和损伤关节,导致炎症和运动丧失的疾病,其特征是炎症性滑膜炎。虽然有效的疾病改善药物的广泛使用增加了RA患者的机会,但骨科手术和全关节置换术仍然是终末期关节治疗的重要选择。膝关节是慢性类风湿关节炎患者最常受影响的关节之一。RA的严重程度从中度疾病到严重的,快速进展的,破坏性的版本,逐渐导致持续的疼痛和关节畸形。尽管最近风湿病学领域的生物制剂和治疗方式取得了进展,但某些最终接受关节手术的RA患者往往会经历进行性关节损伤。尽管这些患者可以进行全膝关节置换术,但由于RA的特殊性,全膝关节置换术后并发症增加,预后较差。它们与手术时间延长有关,特别是导致感染、失血和深静脉血栓形成增加。然而,由于RA患者存在并发症的其他危险因素,因此需要考虑某些关键的术前检查和手术方面,以最大限度地提高该亚组患者的TKA结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Current review of surgical management options for total knee arthroplasty in the rheumatoid knee
Abstract Rheumatoid arthritis (RA) represents a condition that can erode cartilage and damage joints, leading to inflammation and loss of movement, characterized by inflammatory synovitis. While the widespread use of potent disease-modifying medications has increased opportunities for RA patients, orthopedic surgery and complete joint arthroplasty remain an important option in end-stage joint treatment. The knee is one of the most frequently affected joints in chronic rheumatoid arthritis patients. The severity of RA ranges from a moderate illness to a serious, rapidly progressing, destructive version, gradually leading to incessant pain and joint deformity. Despite recent advances in biological agents and therapeutic modalities in the field of rheumatology, certain patients with RA, who ultimately undergo joint surgery, tend to experience progressive joint damage. Though, TKA can be performed in these patients, increased complications and poorer outcomes may result after total knee arthroplasty, because of the particularities given by RA. They are associated with extended operating time, specifically resulting in increased infection, blood loss and deep vein thrombosis. However, because RA patients present additional risk factors for complications, certain critical preoperative examination and surgical aspects need to be considered in order to maximize TKA outcomes in this subgroup of patients.
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