考虑疫苗接种消毒和早期检疫的口蹄疫数学模型

Wahyudin Nur, Darmawati Darmawati, N. Afni, Sriwana Bulawan, Nur Haeni, Abdullah Abdullah, Nirma Nirma, Muhammad Aspar, Salim Salim
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引用次数: 1

摘要

口蹄疫是一种高度传染性疾病,可感染所有偶蹄类动物。口蹄疫是世界上最重要的病毒性传染病之一。这种疾病造成了牲畜生产和贸易方面的国际损失。在这篇文章中,我们建立了一个考虑早期隔离、疫苗接种和消毒干预的山羊养殖场口蹄疫传播的数学模型。所构建的模型被表示为由八个状态变量组成的常微分方程组。我们用新一代矩阵法确定基本复制数。我们的数值模拟结果表明,接种疫苗对控制口蹄疫的传播和降低基本繁殖数具有至关重要的作用。此外,对潜伏和感染山羊进行检疫干预也能有效控制口蹄疫的传播。基本繁殖数也可通过消毒和检疫措施加以抑制。因此,我们建议实施常规的疫苗接种、筛查和消毒方案。此外,应对农民进行教育,使他们有能力识别暴露于口蹄疫病毒的山羊,以便及早进行检疫。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Mathematical Model of Foot and Mouth Disease Considering Vaccination Disinfection And Early Quarantine
Foot and Mouth Disease (FMD) is a highly contagious disease that can infect all cloven hoofed animals. FMD is one of the most important infectious viral diseases in the world. This disease is responsible for international losses in livestock production and trade. In this article, we formulate a mathematical model for the spread of FMD in goat farms that considers early quarantine, vaccination, and disinfection interventions. The model constructed is expressed as a system of ordinary differential equations consisting of eight state variables. We determine the basic reproduction number using the next-generation matrix method. Our numerical simulation results show that vaccination has a very crucial role in controlling the spread of FMD and reducing the basic reproduction number. In addition, quarantine interventions for latent and infectious goats are also effective in controlling the spread of FMD. The basic reproduction number can also be suppressed by disinfection and quarantine interventions. Therefore, we recommend implementing routine vaccination, screening and disinfection programs. In addition, farmer should be given education so that they have the ability to identify goats exposed to FMDV so that quarantine can be carried out early.
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