糖尿病对慢性阻塞性肺病患者肺功能检查的影响

B. Suranjan, Atluri Deekshit, S. BalaYaswanthKumar, Mano Ranjitha Pulivarthi
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摘要

慢性阻塞性肺疾病(COPD)是由肺部对易激颗粒或气体的炎症反应异常引起的一种疾病。这是一种不可逆转的情况,会在以后的岁月中恶化。糖尿病患者发生肺功能异常的风险增加,在慢性阻塞性肺病患者中,糖尿病甚至使病情恶化,高达1.6-16%的慢性阻塞性肺病患者受到糖尿病的影响。许多研究还表明,肺是糖尿病的靶器官,血糖暴露可能是肺功能下降的一个原因。低血糖对呼吸系统的影响主要包括全身性炎症、低氧血症、氧化应激、气体交换改变和肺组织的改变。本研究旨在通过肺活量测定等肺功能测试,评估COPD合并糖尿病患者的肺功能,获取FVC、FEV1、FEV/FVC、PEF值,分析已完成的肺功能障碍水平。患者包括男女,并根据其疾病分为两组,第1组包括COPD,第2组包括COPD合并糖尿病,每组20人。我们的研究结果表明,糖尿病会使COPD患者的肺功能恶化,如果不治疗,还可能导致呼吸衰竭。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effects of Diabetes on pulmonary function tests in COPD Patient
COPD (chronic obstructive pulmonary disease) is a condition caused by abnormalities in the inflammatory responses of the lungs to irritable particles or gases. This is an irreversible condition that progresses in later years.Diabetes patients have an increased risk of developing abnormal lung functioning and also in conditions of COPD it even worsens the condition, up to 1.6-16% of the COPD population were affected due to diabetes mellitus.Many studies also suggest that the lungs are a target organ in diabetes and glycemic exposure may be a causation factor for reduced lung function. Systemic inflammation, hypoxemia, oxidative stress, altered gas exchange, and changes in lung tissues were the major impacts on the respiratory system which were induced by hypoglycemia. In this study, we aimed to assess the lung functioning in COPD patients with diabetes by performing the pulmonary functions test like spirometry by obtaining the values of FVC, FEV1, FEV/FVC, and PEF thereby analyzing the level of lung dysfunction that has been done. Patients were includes of both genders and were divided into two groups depending on their disease group 1 includes COPD and group 2 includes COPD with DM considering twenty members in each group. Our study results show that diabetes worsens the lung functioning in COPD than it already is, it may also cause respiratory collapse if untreated.
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