TNF-α多态性作为特伦加纳地区糖尿病肾病的生物标志物

Owaisul Haq Zamin Ahmed Kaiser Jamil, S. Joshi, K. Jamil
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引用次数: 1

摘要

摘要背景:糖尿病肾病(Diabetic Nephropathy, DN)是长期糖尿病患者的并发症之一。在DN的遗传危险因素中,TNF-α,一种抗炎细胞因子被认为以旁分泌/自分泌方式起作用,并被假设与胰岛素抵抗有关。本研究探讨患者TNF-α基因G - C变异与其他生化参数与DN的关系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Polymorphism of TNF-α as a Biomarker of Diabetic Nephropathy in patients of Telangana Region
Published by Madridge Publishers Abstract Background: Diabetic Nephropathy (DN) is one of the complications in patients with prolonged diabetes. Among the genetic risk factors for DN, TNF-α, an anti-inflammatory cytokine is proposed to act in a paracrine/autocrine manner and is hypothesized to be associated with insulin resistance. In the current study, the relationship of the G ↆC variant of the TNF-α gene in patients, associated with other biochemical parameters with DN was investigated.
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