Future directions of investigation on gamete and gonadal immunology in the male

clinical data, investigation using experimental models of testicular autoimmunity is quite helpful to estimate physiopathology and epidemiology of the spermatogenic disturbance of autoimmune origin. From various results from experimental animals, it appears that although the testis is regarded as an immunologically privileged organ and resistant to inflammation, it is also immunologically fragile and highly susceptible to autoimmune inflammation. In the present review, the author will present future subjects in the field of male reproductive immunology.