人恶性组织中非特异性结合的IgG和Fc γ受体。

F Wesenberg
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引用次数: 0

摘要

在通过破坏组织消除Fc γ受体活性(FcRA)和FcRA完好无损的情况下,在相同组织的洗脱液中发现了相似数量的非特异性结合IgG。这表明非特异性结合的IgG要么没有附着在FcR上,要么只有游离的FcR被清除。在FcRA被清除的组织的上清中未检测到FcRA,表明FcRA被破坏。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Non-specifically bound IgG and Fc gamma receptors in human malignant tissues.

Similar amounts of non-specifically bound IgG were found in the eluates of the same tissues both after the Fc gamma receptor activity (FcRA) had been abolished by disrupting the tissue and when FcRA was intact. This indicates that the non-specifically bound IgG is either not attached to the FcR, or that only the free FcR were abolished. No FcRA was detected in the supernatant of the tissue from which the FcRA was abolished, thus indicating that the FcRA was destroyed.

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