Evaluation of Vitamin D Status, Selenium & CRP Level in Psoriasis

Background: Psoriasis is an inflammatory skin disease that is associated to a number of clinical conditions. It results from a combination of genetic predisposition and environmental factors, which together provoke sensitization of the immune system. We aim to explore the status of serum vitamin D, selenium and CRP levels in patients with psoriasis and their association with the severity of the disease. Materials and Methods: There were 50 psoriasis cases and 47 healthy people in this hospital-based case-control research. The levels of serum VD, selenium, and CRP were measured, as well as the general demographic data. Results: VD levels are considerably lower in psoriasis (p< 0.005) according to statistical analyses. Obesity was found to be more common among psoriasis patients than controls in the demographic factors.The levels of selenium and CRP in the serum did not differ significantly between the two groups. Conclusion: We conclude that vitamin D deficiency is strongly associated with psoriasis. Vitamin D supplementation can help with psoriasis management as well as obesity reduction. Serum selenium and CRP levels have shown very little significance in our study.