SYNTHESIS OF NOBLE METAL NANOPARTICLES AND THEIR USE IN SENSOR DEVICES, PART 1: SYNTHESIS OF Ag, Au NANOPARTICLES

Noble metal nanoparticles are of great importance in the field of biomedicine due to their very diverse applications as antivirals drugs, diagnostic methods, drug carriers and imaging probes. These nanosized materials, in particular gold and silver nanoparticles, are useful as optical probes for detecting a wide range of biological analytes and as promising candidates for the development of highly reliable and ultrasensitive metal nanobiosensors. The success of the practical application nanoparticles depends on the development of safety, simple, efficient, scalable and environmentally friendly synthesis methods. For this has been successfully developed various green protocols using a variety of plant species, algae, fungi, bacteria and other microorganisms. In the first part of this article have been presented information about traditional methods for the synthesis of nanoparticles, with an emphasis on the most common, chemical method, an overview of recent advances in the field of green synthesis of metal nanoparticles involving plants, their likely synthetic mechanism, characterization methods and factors influencing their synthesis. Have been determined the problems of biological synthesis and ways to solve them in the future.