自身抗体检测在儿童系统性红斑狼疮诊断中的意义

Journal of Modern Clinical Medical Bioengineering Pub Date : 2006-04-30 DOI:10.3760/CMA.J.ISSN.1008-634X.2006.02.041

李梅爱, 关克涛, 关启鸿, 仇瑞珍

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摘要

目的探讨抗核抗体(ANA)、抗双链DNA(ds-DNA)、抗ENA抗体检测在儿童系统性红斑狼疮(SLE)诊断中的价值.方法利用酶免疫斑点技术对56例SLE患儿的抗核抗体、抗ds-DNA、抗ENA抗体进行检测.结果56例SLE患儿ANA阳性率最高94.6%,抗ds-DNA阳性率为55.4%,抗Sm/RNP阳性率64.8%,抗SSA/SSB阳性率60.7%.结论SLE患者血清中存在多种自身抗体,自身抗体的联合检测对SLE的诊断和病情的监测有着重要的意义。

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自身抗体检测在儿童系统性红斑狼疮诊断中的意义

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Journal of Modern Clinical Medical Bioengineering

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