用于MEMS微电极阵列神经化学传感的氧化铱参考电极

R. K. Franklin, Matthew D. Johnson, Katharine A. Scott, J. Shim, H. Nam, D. Kipke, Richard B. Brown
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引用次数: 15

摘要

我们首次报道了一种带有集成氧化铱(IrO)准参考电极的微机械硅神经探针,用于神经化学记录。探针具有1.5倍103 mum2 IrO参比电极,1.5倍103 mum2 Pt对电极,三个圆形Pt工作电极和三个用于电记录的圆形IrO电极。为了研究电极尺寸的影响,制作了几种不同尺寸的电极(4 ~ 50 μ m半径)。对探针的体外评价表明,使用Ag/AgCl参比电极和片上IrOx参比电极获得的结果密切相关
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Iridium oxide reference electrodes for neurochemical sensing with MEMS microelectrode arrays
We report for the first time a micromachined, silicon neural probe with an integrated iridium oxide (IrO) quasi reference electrode for neurochemical recordings. The probes have a 1.5 times 103 mum2 IrO reference electrode, a 1.5 times 103 mum2 Pt counter electrode, three circular Pt working electrodes, and three circular IrO electrodes for electrical recording. Several different electrode sizes (4 to 50 mum radius) were fabricated in order to study the effects of electrode size. In vitro evaluation of the probes demonstrated close correlation between results obtained using a Ag/AgCl reference electrode and the on-chip IrOx reference electrode
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