老年人认知障碍的患病率和决定因素:一项基于医院的研究

Abhishek Shukla, A. Shukla, Pankhuri Misra
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摘要

痴呆和认知障碍(CI)是一些与衰老相关的常见问题。然而,除了衰老,很多其他因素也会增加这种风险。在本研究中,评估了在老年医疗保健机构门诊就诊的患者CI患病率及其与不同社会人口统计学和临床因素的相关性。:本研究共纳入240例老年门诊患者(60 ~ 60岁),这些患者从不同的急性疾病中康复或进行随访。危重患者、住院患者和有COVID-19暴露史的患者被排除在研究之外。记录患者的人口统计学和社会概况。采用迷你精神状态检查(MMSE)评估认知能力。MMSE评分<27为CI。单因素资料采用卡方检验,多因素资料采用二元logistic回归分析。患者平均年龄72.58±6.46岁(62 ~ 91岁),男性居多(55%)。CI患病率为41.2%。老年人轻度认知障碍59例(24.6%),中度认知障碍40例(16.7%)。单因素评估发现,年龄较大(p=0.003)、男性(p=0.024)、无配偶生活(p=0.040)和最近一年住院史(p=0.031)与CI显著相关。在logistic回归中,年龄(OR=1.072)、女性(OR=0.561)、日常工作能力(OR=0.461)和住院史(OR=1.823)被确定为CI的独立预测因素。在我们的研究中,CI的患病率为41.2%。年龄、性别、日常工作能力和住院史与CI风险独立相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence and determinants of cognitive impairment in an elderly population: A hospital based study
: Dementia and cognitive impairment (CI) are some of the common problems associated with ageing. However, a lot of other factors apart from ageing can increase this risk. In this study, prevalence of CI and its correlation with different sociodemographic and clinical factors was assessed among patients attending outpatient department of a geriatric healthcare facility.: A total of 240 elderly OPD patients (>60 years) having recovered from different acute illnesses or making follow-up visits were enrolled in the study. Critically ill, hospitalized patients and those with history of COVID-19 exposure were excluded from the study. Demographic and social profile of the patients was noted. Mini Mental State Examination (MMSE) was used for assessment of cognition. MMSE score <27 was considered as CI. Data was analyzed using chi-square test for univariate and binary logistic regression for multivariate assessment. Mean age of patients was 72.58±6.46 years (range 62-91 years), majority of patients were males (55%). Prevalence of CI was 41.2%. There were 59 (24.6%) elderly with mild and 40 (16.7%) with moderate cognitive impairment. On univariate assessment, older age (p=0.003), male sex (p=0.024), living without spouse (p=0.040) and history of hospitalization in last one year (p=0.031) were found to be significantly associated with CI. On logistic regression age (OR=1.072), female sex (OR=0.561), ability to perform routine work (OR=0.461) and hospitalization history (OR=1.823) were identified as independent predictors of CI.: Prevalence of CI was 41.2% in our study. Age, sex, ability to perform routine works and hospitalization history were independently associated with CI risk.
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