三维位置敏感CdTe检测单元在超高分辨率人体PET扫描仪临床应用的基本评价

S. Takyu, K. Ishii, Y. Kikuchi, A. Terakawa, S. Matsuyama, A. Ahmed, T. Matsuyama, K. Takahata, Shinya Igarashi, Y. Sakurada, R. Ito, Yohei Yamamoto
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引用次数: 1

摘要

我们开发了超高分辨率人体PET扫描仪,世界上第一个分辨率小于1毫米,采用CdTe型半导体探测器。本研究的目的是研制构成PET扫描仪的三维位置敏感CdTe探测器单元,并对该扫描仪的基本性能进行评估。在这里,我们报道其发展的进展和结果。作为我们扫描仪的探测器,我们开发了二维位置敏感碲化镉探测器(2D-PSD)。它可以获取探测器内部的相互作用位置,位置分辨率为1.2 mm。通过密集堆叠2D-PSD和后续电路(放大器,ADC和其他处理电路),我们开发了三维位置敏感的CdTe检测器单元。通过将这些探测器单元以十角形放置,我们构建了PET龙门。为了确定扫描仪的工作条件,我们对每个检测器单元进行了评估和改进。我们从结果中确认了每个检测器单元的高性能,但我们发现一些检测器的性能较低,需要更多的改进。我们还可以根据结果确定检测器的工作条件(偏置电压的设定值和每个信号处理)。针对碲化镉探测器的极化现象,研制了偏压复位系统,并根据实验结果确定了其工作条件。接下来我们评估了扫描仪的基本性能。我们在视场中移动一个点源三个方向,并评估基本空间分辨率。最后,我们进行了一些幻像测量,得到了它们幻像的重建图像。通过本课题的研究,可以将扫描仪的发展推进到幻体研究阶段。然而,提高探测器的性能是未来的一个重要问题。我们将继续评估该扫描仪的临床应用性能。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Basic evaluation of three-dimensional position sensitive CdTe detector unit for clinical use of ultra-high resolution human PET scanner
We develop ultra-high resolution human PET scanner with the world's first resolution of less than 1 mm, which is used CdTe type semiconductor detectors. The aim of this study is that we develop three-dimensional position sensitive CdTe detector units which construct PET scanner, and evaluate basic performance of this scanner. Here we report about progress and outcome of its development. As the detector of our scanner, we developed position sensitive CdTe detectors (2D-PSD) two-dimensional . It can acquire interaction position inside the detector with positional resolution of 1.2 mm. By densely stacking 2D-PSD and subsequent circuits (Amplifiers, ADC, and other processing circuits), we developed three-dimensional position sensitive CdTe detector units. By placing these detector units with shape of decagon, we constructed PET gantry. In order to determine the operating conditions of the scanner, we performed evaluation and improvement of each detector unit. We confirmed high performance of each detector unit from their results, but we found out some of detectors indicate low performance and they need more improvement. Also we could determine the operating conditions (Setting values of bias voltage and each signal processing) to detectors from their results. For polarization phenomena of CdTe detector, we developed a bias reset system and decided its operating condition by experimental results. Next we evaluated the basic performance of the scanner.We moved a point source three directions in the field of view, and we evaluated basic spatial resolution. Finally we performed some phantom measurements, and we could obtain reconstruction images of their phantoms. By this research, we could forward development of the scanner to the stage of phantom study. However improvement of detector performance is a significant issue in the future. We will continue to evaluate performance of the scanner for clinical use.
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