ARGUS微型PET虚拟性能评估平台:一种经济的PET扫描仪质量评估方法

L. Shen, Cheng-Han Wu, Jyh-Cheng Chen
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引用次数: 0

摘要

目的:本研究的主要目的是通过GATE, Geant4应用于断层发射模拟的虚拟平台来评估临床前微型PET/CT (ARGUS-SEDECAL)的性能。方法:通过GATE,我们能够准确地再现PET扫描仪的物理特性,包括仪器的参数,以及Argus系统的数据采集系统。通过GATE建立了与ARGUS参数相同的双环探测器。采用18个模块的双层扫描仪,前层为正硅酸镥钇(LYSO)晶体,后层为正硅酸钆(GSO)晶体,模拟扫描仪的几何形状与ARGUS模型完全一致。结果:使用GATE采集的数据,通过计算标准偏差百分比(%STD)来评估图像的均匀性。来自Argus的图像的%STD显示了与我们自己设计的模块相当的结果。结论:本研究表明GATE可以作为一种相对公正实用的PET扫描仪性能评估方法,不需要真正的仪器和物理测试,从而可以成为PET设计和性能评估的一种非常经济有效的方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Virtual performance evaluation platform for ARGUS microPET: An economic approach to PET scanner quality assessment
Purpose: The primary objective of this study was to assess the performance of a preclinical micro PET/CT (ARGUS-SEDECAL) via GATE, Geant4 Application for Tomographic Emission, a virtual platform for tomographic emission simulation. Methods: By using GATE, we were able to accurately reproduce the physics of a PET scanner, including such as the instrument's parameters, and the data collecting system of an Argus system. A dual-ring detector with the same parameters as compared to the ARGUS was set up via GATE. A dual-layer scanner with 18 modules, with lutetium - yttrium orthosilicate (LYSO) front layer and gadolinium orthosilicate (GSO) rear layer crystal, geometry of the simulated scanner all represented that of the ARGUS model. Results: The data collected from GATE was used to evaluate the uniformity of our images, by calculating the percentage standard deviation (%STD). The %STD of images from Argus showed comparable results to our own self designed modules. Conclusions: This study has shown that GATE can serve well as a relatively unbiased and practical method to evaluate performances of PET scanners without the need of having true instrumentation and physical testing, which in turns can be a very cost-effective method to PET design and performance evaluation.
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