{"title":"新型冠状病毒肺炎患者d -二聚体水平与胸部x线评分的关系","authors":"Tersia Viradanti, Yudith Yunia Kusmala","doi":"10.2991/ahsr.k.210723.037","DOIUrl":null,"url":null,"abstract":"—Coronavirus disease is a kind of pneumonia cause by infection of SARS-CoV-2. In most cases, patients only get mild manifestation or even asymptomatic. Some patient can get severe disease, especially elderly people or someone with comorbid, leading to cytokines storm that triggers SIRS and induce coagulation dysregulation (marked by D-dimer elevation) so that increasing risk to get thrombosis. Recent pathology finding suggest that micro-thrombosis has contribution to ARDS due to lung’s fibrosis. We use a CXR scoring system to assess lung parenchyma involvement in COVID-19 patients and D-dimer level to see coagulopathy then performing an analysis to investigate the relationship between both. Based on the Spearman test, we find that there is a significant relationship between D-dimer level and CXR scores of COVID-19 patients describe as a positive correlation (p=0.023; r=0.358).","PeriodicalId":346010,"journal":{"name":"Proceedings of the 12th Annual Scientific Meeting, Medical Faculty, Universitas Jenderal Achmad Yani, International Symposium on \"Emergency Preparedness and Disaster Response during COVID 19 Pandemic\" (ASMC 2021)","volume":"35 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Relation Between D-dimer Level and Chest X-Ray (CXR) Scoring in COVID-19 Patients:\",\"authors\":\"Tersia Viradanti, Yudith Yunia Kusmala\",\"doi\":\"10.2991/ahsr.k.210723.037\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"—Coronavirus disease is a kind of pneumonia cause by infection of SARS-CoV-2. In most cases, patients only get mild manifestation or even asymptomatic. Some patient can get severe disease, especially elderly people or someone with comorbid, leading to cytokines storm that triggers SIRS and induce coagulation dysregulation (marked by D-dimer elevation) so that increasing risk to get thrombosis. Recent pathology finding suggest that micro-thrombosis has contribution to ARDS due to lung’s fibrosis. We use a CXR scoring system to assess lung parenchyma involvement in COVID-19 patients and D-dimer level to see coagulopathy then performing an analysis to investigate the relationship between both. Based on the Spearman test, we find that there is a significant relationship between D-dimer level and CXR scores of COVID-19 patients describe as a positive correlation (p=0.023; r=0.358).\",\"PeriodicalId\":346010,\"journal\":{\"name\":\"Proceedings of the 12th Annual Scientific Meeting, Medical Faculty, Universitas Jenderal Achmad Yani, International Symposium on \\\"Emergency Preparedness and Disaster Response during COVID 19 Pandemic\\\" (ASMC 2021)\",\"volume\":\"35 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1900-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Proceedings of the 12th Annual Scientific Meeting, Medical Faculty, Universitas Jenderal Achmad Yani, International Symposium on \\\"Emergency Preparedness and Disaster Response during COVID 19 Pandemic\\\" (ASMC 2021)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2991/ahsr.k.210723.037\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the 12th Annual Scientific Meeting, Medical Faculty, Universitas Jenderal Achmad Yani, International Symposium on \"Emergency Preparedness and Disaster Response during COVID 19 Pandemic\" (ASMC 2021)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2991/ahsr.k.210723.037","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The Relation Between D-dimer Level and Chest X-Ray (CXR) Scoring in COVID-19 Patients:
—Coronavirus disease is a kind of pneumonia cause by infection of SARS-CoV-2. In most cases, patients only get mild manifestation or even asymptomatic. Some patient can get severe disease, especially elderly people or someone with comorbid, leading to cytokines storm that triggers SIRS and induce coagulation dysregulation (marked by D-dimer elevation) so that increasing risk to get thrombosis. Recent pathology finding suggest that micro-thrombosis has contribution to ARDS due to lung’s fibrosis. We use a CXR scoring system to assess lung parenchyma involvement in COVID-19 patients and D-dimer level to see coagulopathy then performing an analysis to investigate the relationship between both. Based on the Spearman test, we find that there is a significant relationship between D-dimer level and CXR scores of COVID-19 patients describe as a positive correlation (p=0.023; r=0.358).