大鼠产前一氧化碳诱发电位和成年诱发电位。

Journal of environmental science and health. Part C: Environmental health sciences Pub Date : 1979-01-01

R S Dyer, U Eccles, H S Swartzwelder, L D Fechter, Z Annau

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引用次数: 0

摘要

在出生前暴露于轻度一氧化碳缺氧的大鼠成年后进行了研究。记录未麻醉暴露大鼠和对照大鼠视觉皮层在四种不同闪光强度下的闪现诱发电位。co暴露雌性大鼠闪现诱发电位的P1-N1和N1-P2分量的振幅均显著高于对照组。因此，实验表明，暴露于相对轻度的一氧化碳水平会导致中枢神经系统功能的长期改变。

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Prenatal carbon monoxide and adult evoked potentials in rats.

Hooded rats prenatally exposed to mild carbon monoxide hypoxia were studied as adults. Flash evoked potentials were recorded from the visual cortex of unanesthetized exposed and control rats at four different flash intensities. The amplitude of bothe the P1-N1 and N1-P2 components on the flash evoked potential were significantly greater in CO-exposed female rats than in control females. The experiments thus demonstrate long term alterations in CNS function from exposure to relatively mild levels of CO.

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Journal of environmental science and health. Part C: Environmental health sciences

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