氮化硅纳米孔的制备与表征

Lingzhi Wu, Hang Liu, Yuqi Liu, Hao Chen, Quanjun Liu, Zuhong Lu
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引用次数: 0

摘要

纳米孔已成为单分子水平分子检测的重要工具。在我们的工作中,制备了氮化硅膜的固体纳米孔并通过实验对其进行了表征。首先,设计了独立的氮化硅膜,并采用精细的工艺进行蚀刻。然后,用聚焦离子束在独立膜上钻孔。通过聚焦离子束作用时间的不同,制备了一组不同直径和形状的纳米孔。这些纳米孔显示出高质量的形貌和电信号。除了DNA外,随着单个DNA分子通过孔的易位,还会出现一系列明显的阻滞电流。该结果将为单分子传感纳米孔器件的工程设计提供启示。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Fabrication and characterization of silicon nitride nanopore
Nanopores have become an important tool for molecule detection at single molecular level. In our work, the solid nanopore in silicon nitride membranes are fabricated and characterized by experiments. Firstly, the free-standing silicon nitride membranes are designed and etched by delicate techniques. Then, the free-standing membranes are drilled by focus ion beam. A set of nanopores with varied diameters and shapes are fabricated by different acting time of focused ion beam. These nanopores display the high quality of morphologies and electric signals. In addition of DNA, a series of evident block currents appear corresponding to the translocation of single DNA molecule through the pore. The results will shed light on the engineering of nanopore devices for single-molecule sensing.
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