基于计算序列变异的贪婪遗传算法优化基因功能预测速度

A. Kheirkhah, S. Daud, K. Kamardin, N. M. Noor, A. Azizan, Y. Yusuf
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引用次数: 0

摘要

遗传算法在多种复杂情况下具有较强的鲁棒性,其关键在于它采用交叉和变异技术,可以灵活地生成多个种群。这在解决像计算DNA序列变异这样的难题中得到了体现,这种问题可以用简单的遗传算法很容易地解决。然而,实现一个快速和优化的算法来生成任何顺序的复制是一个时间和成本问题。本文的主要贡献是对遗传算法(GA)选择阶段的优化,提出了一种新的贪心算法和遗传算法的混合算法来计算DNA序列变异。这是通过贪心算法和遗传算法的结合来实现的,目的是在选择段上挑选出最合适的父母。然后,将适应度函数与贪心算法相结合,通过遗传算法减少网络内的节点数量,优化选择段的速度。与其他知名算法相比,该方法将复杂度优化到O(nlogn)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Optimize Velocity of Gene Function Prediction by Using Greedy-Genetic Algorithm on Computational Sequence Variants
The point which makes the Genetic Algorithm so robust in many kinds of complex situations is its flexibility to generate many populations by employing the crossover and mutation techniques. This is shown in solving a difficult problem like the computational DNA sequence variant which can be easily solved by applying a simple Genetic Algorithm. However, achieving a fast and optimized algorithm to generate any order of reproduction is a matter of time and cost. The main contribution of this paper is on the optimization in the selection stage of the Genetic Algorithm (GA) that proposes to build a new hybrid of the Greedy and the Genetic Algorithms for the computation of DNA sequences variant. This is achieved by integrate Greedy and Genetic algorithm, aim to pick up the most suitable parents on selection segment. Sequentially, fitness function combined with greedy algorithm is applied to reduce the number of node within the network and optimize the velocity of selection segment through genetic algorithm. In comparison with other well-known algorithm, this method optimized the complexity into O(nlogn).
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