儿童甲状腺弹性成像

M. Pykov, N. Kuzmina, N. Rostovtsev
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摘要

本研究的目的是在不同性别和年龄组的儿童中使用剪切波弹性成像和弹性测量法研究未改变甲状腺的刚度。对175名3 ~ 17岁激素正常的儿童进行了检查,其中80名女孩,95名男孩。所有儿童均在“仰卧”位接受甲状腺超声检查,并在aiexplorer设备(Supersonic Imagine, France)上使用5-18 MHz频率范围的线性传感器进行二维横波弹性成像。对甲状腺左右叶的杨氏模量进行了5次测量。使用Multi Q-box软件,自动确定每个分数的杨氏模量(E):平均值(Emean),最大值(Emax),最小值(Emin),标准差(SD)。该研究证实,随着年龄的增长,儿童甲状腺僵硬度值有统计学意义的增加,甲状腺左右叶僵硬度有统计学意义的差异(p = 0.003),甲状腺僵硬度无性别差异(男孩中位Emean为7.40 kPa,女孩中位Emean为6.80 kPa;P = 0.170)。作者提供的剪切波弹性成像技术可以成为评估儿童甲状腺状况的附加诊断工具。不同年龄组儿童甲状腺组织硬度的既定值可推荐用于甲状腺病理的及时诊断。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
THYROID ELASTOGRAPHY IN CHILDREN
The aim of the research was to study the stiffness of an unchanged thyroid gland using shear wave elastography with elastometry in children in different gender and age groups. 175 children with normal hormonal status aged from 3 to 17 were examined, 80 of them were girls and 95 boys. All children underwent ultrasound examination of the thyroid gland in the "supine" position of the examinees, supplemented by two-dimensional shear wave elastography on Aixplorer apparatus (Supersonic Imagine, France) using a linear sensor in the frequency range of 5-18 MHz. Five measurements of Young's modulus value of the right and left lobes of the thyroid gland were carried out. Using Multi Q-box software, the following values of Young's modulus (E) for each fraction were automatically determined: the mean (Emean), the maximum (Emax), the minimum (Emin), the standard deviation (SD). The study established a statistically significant increase in thyroid stiffness values in children with increasing age, statistically significant differences in the stiffness of thyroid right and left lobes (p = 0.003), the absence of gender differences in thyroid stiffness (median Emean in boys – 7.40 kPa, in girls – 6.80 kPa; p = 0.170). The technique of shear wave elastography that is offered by the authors can become an additional diagnostic tool in assessing the condition of the thyroid gland in children. The established values of thyroid tissue stiffness in children of different age groups can be recommended to be used for the purpose of timely diagnosis of thyroid pathology.
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