联合外用草药乳膏对初产妇妊娠纹的发生率和严重程度的影响:一项随机临床试验

S. Alirezaei, M. Yazdanpanah, H. Esmaeili, N. Khadem, Naghmeh Zabolinejad, F. Sadeghi, R. L. Roudsari
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引用次数: 0

摘要

妊娠纹,发生在大多数怀孕中,对妇女来说是不愉快的,治疗费用昂贵。这种情况的预防措施是使用草药油来保持皮肤的弹性。目前的研究调查了局部联合草药乳膏对初产妇妊娠纹的发生和严重程度的影响。在这项三盲随机临床试验中,90名在伊朗马什哈德医疗中心接受治疗的妊娠头三个月的初产妇被随机分为两组,分别使用草药乳膏和安慰剂,其中54人完成了研究。干预组在妊娠14-16周至27-30周期间,接受0.3 g乳霜,局部由金盏菊、洋甘菊、天竺葵、可可油和大豆组成,每周3天,每天2次。安慰剂组接受保湿乳霜。孕龄38 ~ 40周时,采用Atwal数值评分系统和数码摄影对腹部皮肤纹的发生率和严重程度进行评估。干预组与安慰剂组的条纹患病率差异有统计学意义(43.3% vs 87.5%) (P<0.0001)。此外,两组之间在条纹的严重程度方面也有显著差异(P < 0.001)。在干预组中,86.7%、13.3%和0%的病例出现轻度、中度和重度纹痕,而在安慰剂组中,37.5%、58.3%和4.2%的病例出现轻度、中度和重度纹痕。考虑到局部应用的草药乳膏,建议卫生保健提供者建议孕妇使用草药乳膏,以避免妊娠纹的发展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The effect of a combined topical herbal cream on the incidence and severity of pregnancy striae in primiparous women: A randomized clinical trial
Striae gravidarum, which occurs in most pregnancies, is unpleasant for women, and its treatment is costly. A preventive measure for this condition is applying herbal oils to maintain the skin's elasticity. The current study investigates the effect of a topical combined herbal cream on the occurrence and severity of striae gravidarum in primiparous women. In this triple blind randomized clinical trial, 90 primiparous women at their first trimester of pregnancy, attending healthcare centres in Mashhad, Iran, were randomly allocated into two groups of herbal cream and placebo, from which 54 completed the study. The intervention group received 0.3 g of the cream,topically, composed of Calendula (Pot marigold), Anthemis nobilis (Chamomile), Pelargonium Graveolens (Rose Geranium), Theobroma oil (Cocoa Butter) and Soybean, twice a day for three days a week from 14-16 to 27-30 weeks of gestation and the placebo group received a moisturizer cream. At the gestational age of 38—40 weeks, the incidence and severity of striae on the abdominal skin were evaluated using the Atwal numerical scoring system and digital photography. There was a significant difference between the prevalence of striae in the intervention and placebo group (43.3% vs 87.5%) (P<0.0001). Also a significant difference was seen between two groups in terms of severity of the striae (P < 0.001). In the intervention group the severity of striae in 86.7%, 13.3%, and 0% of the cases was mild, moderate, and severe, respectively, whereas, in the placebo group it was occurred as mild, moderate, and severe in 37.5%, 58.3%, and 4.2% of the cases. Considering the topically applied herbal cream, it is recommended that health care providers suggest the pregnant women to use herbal creams to avoid striae gravidarum development.
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