儿童和青少年低能量长骨骨折骨密度的研究结果

Z. Matanov, F. Umarov
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摘要

目的:确定儿童和青少年长骨骨折的骨矿物质密度的初始指标,以评估维生素d的状况。本文对46例6 ~ 18岁长骨骨折患儿(男童39例(84.8%),女童7例(15.2%))进行了密度测量和实验室方法的研究。骨密度采用双能x线骨密度仪评估,骨密度仪采用欧亚规范数据库。结果。9例骨折患儿出现I级骨质减少,1例II级骨质减少,5例I级骨质疏松,其余31例骨密度指标均正常。56.4%的男孩和57.1%的女孩钙含量低,94.8%的男孩和100%的女孩碱性磷酸酶活性增加,证明骨骼形成受损。结果显示,61.5%的男生和57.1%的女生缺乏维生素d。低骨密度,低能量骨折儿童和青少年中维生素D缺乏症的存在,鉴于这些指标对骨折愈合的重要性,需要纠正已发现的违规行为:选择更温和的治疗方法,预约适当的药物治疗,动态监测处方治疗的有效性,并在确诊为骨质疏松症的儿童中-动态研究骨密度。关键词:骨密度,长骨低能骨折,维生素D缺乏症,骨质疏松症,儿童青少年骨折,乌兹别克斯坦
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Results of a Study of Bone Mineral Density in Children and Adolescents with Low-energy Fractures of Long Bones
The aim: to determine the initial indicators of bone mineral density in children and adolescents with fractures of long bones, to assess the status of vitamin D. Methods. We studied the data of densitometric and laboratory methods of studying 46 sick children (39 (84.8%) boys and 7 (15.2%) girls) with long bone fractures at the age from 6 to 18 years. Bone mineral density was assessed by the method of dual-energy X-ray absorptiometry on a bone densitometer using the Eurasian regulatory database. Results. In 9 sick children with fractures, osteopenia of the I degree was revealed, in one patient - osteopenia of the II degree, in 5 patients - osteoporosis of the I degree, in the remaining 31 children the indicators of bone mineral density corresponded to normal values. Low calcium levels in 56.4% of boys and 57.1% of girls, along with increased alkaline phosphatase activity in 94.8% of boys and 100% of girls, testified to impaired bone formation. The results showed that 61.5% of boys were deficient and 57.1% of girls were deficient in vitamin D. Conclusion. Low bone mineral density, the presence of hypovitaminosis D in children and adolescents with low-energy fractures, given the importance of these indicators for fracture healing, require correction of the revealed violations: the choice of more gentle treatment methods, the appointment of adequate drug therapy, dynamic monitoring of the effectiveness of the prescribed therapy, and in children with a confirmed diagnosis of osteoporosis - studies of bone mineral density in dynamics. Key words: bone mineral density, low-energy fractures of long bones, hypovitaminosis D, osteoporosis, fractures in children and adolescents, Uzbekistan.
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