呼吸声音作为筛查传染性肺部疾病的生物标志物

Harini Senthilnathan, Parijat Deshpande, B. Rai
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引用次数: 3

摘要

定期监测呼吸音对于早期筛查阻塞性上呼吸道感染(如通常由病毒引起的气道炎症)至关重要。作为立即的第一步,需要检测呼吸音的异常。成年男性的平均肺活量约为6升,不幸的是,肺部疾病的表现直到疾病发展到严重阶段时才被发现。此外,由于病毒感染而引起的这种快速进展的疾病需要通过非定音呼吸音检测到以立即采取治疗行动,因此需要经常监测。这些检查通常由训练有素的医生通过听诊器进行,这需要亲自到医院进行检查。在COVID-19等大流行情况下,现有的医疗基础设施很难对大量人群进行定期筛查。幸运的是,智能手机无处不在,甚至在医患比例失衡的发展中国家,每家每户都有智能手机。考虑到这种技术的可访问性,我们提出了一种基于智能手机的解决方案,通过用户智能手机的内置麦克风和我们基于人工智能(AI)的异常检测引擎来监测用户的呼吸声音。本文提出的异常呼吸音自动分类器能够检测出呼吸功能障碍早期阶段的异常情况,其准确率为95%,并且可以标记这些异常,从而提高了早期发现的可能性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Breath sounds as a biomarker for screening infectious lung diseases
Periodic monitoring of breath sounds is essential for early screening of obstructive upper respiratory tract infections, such as inflammation of the airway typically caused by viruses. As an immediate first step, there is a need to detect abnormalities in breath sounds. The adult average male lung capacity is approximately 6 liters and the manifestation of pulmonary diseases, unfortunately, remains undetected until their advanced stages when the disease manifests into severe conditions. Additionally, such rapidly progressing conditions, which arise due to viral infections that need to be detected via adventitious breath sounds to take immediate therapeutic action, demand frequent monitoring. These tests are usually conducted by a trained physician by means of a stethoscope, which requires an in-person visit to the hospital. During a pandemic situation such as COVID-19, it is difficult to provide periodic screening of large volumes of people with the existing medical infrastructure. Fortunately, smartphones are ubiquitous, and even developing countries with skewed doctor-to-patient ratios typically have a smartphone in every household. With this technology accessibility in mind, we present a smartphone-based solution that monitors breath sounds from the user via the in-built microphone of their smartphone and our Artificial Intelligence (AI) -based anomaly detection engine. The presented automated classifier for abnormal breathing sounds is able to detect abnormalities in the early stages of respiratory dysfunctions with respect to their individual normal baseline vesicular breath sounds, with an accuracy of 95%, and it can flag them, and thus enhances the possibility of early detection.
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