炎症和炎症标志物的观点

N. Johnkennedy, Okafor Chibuzor Mercy
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引用次数: 1

摘要

冠心病的进展和发生可部分归因于炎症的存在。由于我们对炎症分子基础的理解,我们已经确定了可能作为动脉粥样硬化新治疗靶点的标志物。有或没有心血管疾病史的个体可以从监测他们的c反应蛋白(CRP)水平(CVD)中获益。他汀类药物的抗炎特性最近被探索,它们已被证明可以显著降低心血管发病率和死亡率。c反应蛋白、脂联素、CD40配体和脂蛋白相关磷脂酶A是本综述的重点,该综述还研究了他汀类药物对这些生物标志物的影响及其与心血管事件的潜在联系,所有这些生物标志物都被认为参与导致动脉粥样硬化血栓形成和其他心血管疾病的炎症过程。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Perspective of Inflammation and Inflammation Markers
Progression and occurrence of coronary heart disease can be attributed in part to the presence of inflammation. As a result of our understanding of inflammation's molecular underpinnings, we have identified markers that may also serve as new treatment targets for atherosclerosis. Individuals with and without a history of cardiovascular disease can benefit from monitoring their C-reactive protein (CRP) levels (CVD). The anti-inflammatory characteristics of statins have lately been explored, and they have been shown to significantly lower cardiovascular morbidity and death. C-reactive protein, adiponectin, CD40 ligand, and lipoprotein-associated phospholipase A were the focus of this review, which also looked at statins' effect on these biomarkers and their potential link to cardiovascular events, all of which are thought to be involved in the inflammatory process that leads to atherothrombosis and other cardiovascular diseases.
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