表皮生长因子-聚己内酯纳米纤维伤口愈合网头的研制

2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS) Pub Date : 2017-06-18 DOI:10.1109/TRANSDUCERS.2017.7994319

Wei-Chih Lin, Chieh-Shan Wu, I. Yeh

{"title":"表皮生长因子-聚己内酯纳米纤维伤口愈合网头的研制","authors":"Wei-Chih Lin, Chieh-Shan Wu, I. Yeh","doi":"10.1109/TRANSDUCERS.2017.7994319","DOIUrl":null,"url":null,"abstract":"The biocompatible PCL2b200 nanofibre mesh and beads containing epidermal growth factor (EGF) were fabricated separately by using our developed electrospinning and electrospray process for the tissue regeneration applications. The drug release behaviours of two fabricated EGF nano-scaffolds were characterized for 448 hours. The EGF nanofibre mesh performed the quicker released speed and higher release amount than beads. Due to the influence of released EGF, nanofibre mesh also reveals a better proliferation and cell viability than beads that was proved by using the MTT assay.","PeriodicalId":174774,"journal":{"name":"2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS)","volume":"15 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2017-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Development of epidermal growth factor-polycaprolactone nanofiber mesh and bead for wound healing\",\"authors\":\"Wei-Chih Lin, Chieh-Shan Wu, I. Yeh\",\"doi\":\"10.1109/TRANSDUCERS.2017.7994319\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The biocompatible PCL2b200 nanofibre mesh and beads containing epidermal growth factor (EGF) were fabricated separately by using our developed electrospinning and electrospray process for the tissue regeneration applications. The drug release behaviours of two fabricated EGF nano-scaffolds were characterized for 448 hours. The EGF nanofibre mesh performed the quicker released speed and higher release amount than beads. Due to the influence of released EGF, nanofibre mesh also reveals a better proliferation and cell viability than beads that was proved by using the MTT assay.\",\"PeriodicalId\":174774,\"journal\":{\"name\":\"2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS)\",\"volume\":\"15 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-06-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/TRANSDUCERS.2017.7994319\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/TRANSDUCERS.2017.7994319","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

采用静电纺丝和电喷雾技术分别制备了具有生物相容性的PCL2b200纳米纤维网和含有表皮生长因子(EGF)的纳米纤维珠，用于组织再生。对两种制备的EGF纳米支架在448小时内的药物释放行为进行了表征。EGF纳米纤维网比微球具有更快的释放速度和更高的释放量。由于释放的EGF的影响，纳米纤维网也显示出比微珠更好的增殖和细胞活力，这是通过MTT试验证明的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Development of epidermal growth factor-polycaprolactone nanofiber mesh and bead for wound healing

The biocompatible PCL2b200 nanofibre mesh and beads containing epidermal growth factor (EGF) were fabricated separately by using our developed electrospinning and electrospray process for the tissue regeneration applications. The drug release behaviours of two fabricated EGF nano-scaffolds were characterized for 448 hours. The EGF nanofibre mesh performed the quicker released speed and higher release amount than beads. Due to the influence of released EGF, nanofibre mesh also reveals a better proliferation and cell viability than beads that was proved by using the MTT assay.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS)

自引率

0.00%

发文量