St. Ratnah, Alfrida Monica Salasa, Dwi Rachmawaty Daswi, Arisanty Arisanty
{"title":"Potensi Antibakteri Ekstrak Etanol Daun Pegagan (Centella asiatica (L.) Urban) Terhadap Pertumbuhan Enterococcus faecalis dan Citrobacter freundii","authors":"St. Ratnah, Alfrida Monica Salasa, Dwi Rachmawaty Daswi, Arisanty Arisanty","doi":"10.32382/mf.v18i1.2666","DOIUrl":null,"url":null,"abstract":"Enterococcus faecalis and Citrobacter freundii are bacteria that can be found in the digestive sistem like Escherichia coli and can enter the digestive tract with food and drinks containing these bacteria. The phytochemical content of Pegagan Leaves (Centella asiatica (Linn.) Urban) is tannins, flavonoids, steroids, terpenoids, and alkaloids, which have been shown to have antibacterial activity. The purpose of this study was to determine the antibacterial potential of the ethanol extract of Pegagan Leaf (Centella asiatica (L.) Urban.) on the growth of Enterococcus faecalis and Citrobacter freundii. Pegagan leaf simplicia was extracted using the maceration method with 96% ethanol as a solvent, then tested for its antibacterial potential using the disc diffusion method. The results showed that the optimal concentration of ethanol extract of Gotu kola for both test bacteria was 8%. The conclusion of this study, ethanol extract of Pegagan Leaf has antibacterial potential against Enterococcus faecalis and Citrobacter freundii.","PeriodicalId":190256,"journal":{"name":"Media Farmasi","volume":"57 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Media Farmasi","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32382/mf.v18i1.2666","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
粪肠球菌和弗氏柠檬酸杆菌是像大肠杆菌一样可以在消化系统中发现的细菌,可以通过含有这些细菌的食物和饮料进入消化道。积雪草(Centella asiatica, Linn.)的植物化学成分是单宁、类黄酮、类固醇、萜类和生物碱,它们已被证明具有抗菌活性。本研究旨在研究积雪草(Centella asiatica, L.) Pegagan叶乙醇提取物的抑菌潜力。粪肠球菌和弗氏柠檬酸杆菌的生长。以96%乙醇为溶剂,采用浸渍法提取桃根叶,并采用圆盘扩散法检测其抑菌活性。结果表明,两种试验菌的最佳提取液浓度均为8%。综上所述,Pegagan叶乙醇提取物对粪肠球菌和弗氏柠檬酸杆菌具有一定的抑菌作用。
Potensi Antibakteri Ekstrak Etanol Daun Pegagan (Centella asiatica (L.) Urban) Terhadap Pertumbuhan Enterococcus faecalis dan Citrobacter freundii
Enterococcus faecalis and Citrobacter freundii are bacteria that can be found in the digestive sistem like Escherichia coli and can enter the digestive tract with food and drinks containing these bacteria. The phytochemical content of Pegagan Leaves (Centella asiatica (Linn.) Urban) is tannins, flavonoids, steroids, terpenoids, and alkaloids, which have been shown to have antibacterial activity. The purpose of this study was to determine the antibacterial potential of the ethanol extract of Pegagan Leaf (Centella asiatica (L.) Urban.) on the growth of Enterococcus faecalis and Citrobacter freundii. Pegagan leaf simplicia was extracted using the maceration method with 96% ethanol as a solvent, then tested for its antibacterial potential using the disc diffusion method. The results showed that the optimal concentration of ethanol extract of Gotu kola for both test bacteria was 8%. The conclusion of this study, ethanol extract of Pegagan Leaf has antibacterial potential against Enterococcus faecalis and Citrobacter freundii.