微动脉瘤自动检测诊断糖尿病视网膜病变的研究进展

D. Mythily, K. Vidya
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引用次数: 0

摘要

慢性高血糖症是由糖尿病引起的,糖尿病引起分子过程的连锁反应,导致微血管损伤。微血管问题,如糖尿病视网膜病变是糖尿病失明的主要原因。患有慢性高血糖的人必须定期进行眼科检查,以确保他们没有出现任何眼部问题。当糖尿病管理不善时,视网膜血管会受到代谢变化和血流动力学改变的影响,导致持续缺氧。由于视网膜是一个代谢活跃的组织,需要足够的氧合,因此人们正在努力通过过度表达VEGF蛋白等机制来对抗视网膜缺氧。最后,NPDR的病理过程:视网膜毛细血管微动脉瘤,血管通透性和毛细血管关闭,是这些无果而终的尝试的结果。在此,我们总结了一些最新发表的关于微动脉瘤自动检测诊断糖尿病视网膜病变(DRD)的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Survey on Diabetic Retinopathy Diagnosis by Automated Detection of Microaneurysm
Chronic hyperglycemia is caused by diabetes, which causes a chain reaction of molecular processes that results in microvascular damage. Microvascular problems like diabetic retinopathy are the leading cause of diabetic blindness. A person with chronic hyperglycemia must have regular eye exams to ensure they are not developing any eye problems. When diabetes is poorly managed, the retinal vasculature is affected by metabolic changes and altered hemodynamics, resulting in persistent hypoxia. Because the retina is a metabolically active tissue that requires adequate oxygenation, efforts are being made to combat retinal hypoxia via mechanisms such as the overexpression of the VEGF protein. In the end, the pathological processes of NPDR: retinal capillary microaneurysms, vascular permeability, and capillary closure, are the outcome of these fruitless attempts. Here, we have summarized some of the most recent published research on Diabetic Retinopathy Diagnosis by Automated Detection of Microaneurysm (DRD).
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